Protein Info for CSW01_16615 in Vibrio cholerae E7946 ATCC 55056

Annotation: type II toxin-antitoxin system RelE/ParE family toxin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 75 96 PF05016: ParE_toxin" amino acids 6 to 85 (80 residues), 56.9 bits, see alignment E=2.5e-19 PF15781: ParE-like_toxin" amino acids 10 to 83 (74 residues), 33.2 bits, see alignment E=4.2e-12

Best Hits

Swiss-Prot: 54% identical to RELX_ECOLX: Putative RelE-like toxin protein from Escherichia coli

KEGG orthology group: K06218, RelE protein (inferred from 100% identity to vco:VC0395_0794)

MetaCyc: 52% identical to Qin prophage; mRNA interferase toxin RelE (Escherichia coli K-12 substr. MG1655)
3.1.26.-

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (96 amino acids)

>CSW01_16615 type II toxin-antitoxin system RelE/ParE family toxin (Vibrio cholerae E7946 ATCC 55056)
MMTYKLKFLPAAQKEWSKLAPTIQSQFKKKLKERLENPHVPSAKLRGYDAVYKIKLRTAG
YRLAYEVIDDEIVVYVLAVGKRDKDAVYKKLASRFG