Protein Info for CSW01_15115 in Vibrio cholerae E7946 ATCC 55056

Annotation: iron(III) ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 312 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 46 to 64 (19 residues), see Phobius details amino acids 76 to 95 (20 residues), see Phobius details amino acids 101 to 119 (19 residues), see Phobius details amino acids 127 to 150 (24 residues), see Phobius details amino acids 176 to 195 (20 residues), see Phobius details amino acids 208 to 227 (20 residues), see Phobius details amino acids 230 to 251 (22 residues), see Phobius details amino acids 263 to 281 (19 residues), see Phobius details amino acids 287 to 305 (19 residues), see Phobius details PF01032: FecCD" amino acids 8 to 306 (299 residues), 223.8 bits, see alignment E=1.4e-70

Best Hits

Swiss-Prot: 45% identical to YCLN_BACSU: Petrobactin import system permease protein YclN (yclN) from Bacillus subtilis (strain 168)

KEGG orthology group: K02015, iron complex transport system permease protein (inferred from 100% identity to vco:VC0395_1000)

Predicted SEED Role

"Ferric vibriobactin, enterobactin transport system, permease protein VctD (TC 3.A.1.14.6)" in subsystem Iron acquisition in Vibrio (TC 3.A.1.14.6)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (312 amino acids)

>CSW01_15115 iron(III) ABC transporter permease (Vibrio cholerae E7946 ATCC 55056)
MKKLLLVLVVISFCSLFVGVGNLSLAALFQGDESAWQLLLTSRVPRLLAILLSGAGLSIA
GLIMQQVSQNRFASPSTSGTIECAMLGYVLSLVLFGHGQNLWLIFGVSMLGTLVFVFFIQ
RIQFKNVIFVPLIGIIFGNVIDSLATFIAYKYDAIQNLSGWAVANFANLLKGDFELLYIA
IPVAIFSYLYAARISAVGMGKDFATNLGLNYQQVMIIGVALVSIMSATVVMIVGQLPFLG
LIVPNLVSLYYGDNLRKNIPRTAIFGAMFVLLCDLVGRVIIFPYEVPISMIISILGGSVF
IALILRGQRHAG