Protein Info for CSW01_15090 in Vibrio cholerae E7946 ATCC 55056

Annotation: lipase chaperone

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 284 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF03280: Lipase_chap" amino acids 86 to 270 (185 residues), 147.3 bits, see alignment E=2.7e-47

Best Hits

Swiss-Prot: 100% identical to LIFO_VIBCM: Lipase chaperone (lifO) from Vibrio cholerae serotype O1 (strain M66-2)

KEGG orthology group: None (inferred from 100% identity to vcj:VCD_000031)

Predicted SEED Role

"Lipase activator protein, Lipase-specific foldase" in subsystem Cytolysin and Lipase operon in Vibrio

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (284 amino acids)

>CSW01_15090 lipase chaperone (Vibrio cholerae E7946 ATCC 55056)
MKKIAWSLGILVTIGALCAIVWPSWYPSRPLVTTPSQADIQADQSSPRDLLEYFLSGLGE
TSLPVIQQQVQRYEQENQGLLIDSSLFAQYVQYKAALSELTLPQASGGLSTQEWWQLHQS
LLDLQARYFSAEQQALFAEENRLRELAIEKRRIYEQYGQSEEAQRAWQALLLDQPDFIQR
SEATAQLLPQLTQAGQGDTQQRYLARVALVGEQGAQRLAELDDSRATFEQQFQDYYQARA
AILVRNELSASEQQTQIQQLREQHFAPEQWRRIDALERLKDNGE