Protein Info for CSW01_14765 in Vibrio cholerae E7946 ATCC 55056

Annotation: cation:proton antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 103 transmembrane" amino acids 18 to 40 (23 residues), see Phobius details amino acids 48 to 67 (20 residues), see Phobius details amino acids 74 to 97 (24 residues), see Phobius details PF04066: MrpF_PhaF" amino acids 45 to 96 (52 residues), 66.2 bits, see alignment E=1.4e-22

Best Hits

Swiss-Prot: 36% identical to MNHF1_STAHJ: Na(+)/H(+) antiporter subunit F1 (mnhF1) from Staphylococcus haemolyticus (strain JCSC1435)

KEGG orthology group: K05570, multicomponent Na+:H+ antiporter subunit F (inferred from 100% identity to vch:VCA0153)

Predicted SEED Role

"Na(+) H(+) antiporter subunit F" in subsystem Sodium Hydrogen Antiporter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (103 amino acids)

>CSW01_14765 cation:proton antiporter (Vibrio cholerae E7946 ATCC 55056)
MVLKNGYWRSLVDNSLPLAIHFAYLGLLLSLAMAFIRLVLGPSLADRVVALDLISFITIG
FIVVYSLDSGQQTLLDIALTLGLVAFLGTIAFARFIAKRKGEL