Protein Info for CSW01_14715 in Vibrio cholerae E7946 ATCC 55056

Annotation: sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 684 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 267 to 286 (20 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 307 to 432 (126 residues), 49.2 bits, see alignment E=2.9e-17 PF13426: PAS_9" amino acids 321 to 424 (104 residues), 33.7 bits, see alignment E=5.4e-12 PF02518: HATPase_c" amino acids 575 to 683 (109 residues), 86.2 bits, see alignment E=3.2e-28 PF14501: HATPase_c_5" amino acids 579 to 668 (90 residues), 27.5 bits, see alignment E=3.9e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to vch:VCA0141)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (684 amino acids)

>CSW01_14715 sensor histidine kinase (Vibrio cholerae E7946 ATCC 55056)
MKLNKASWIVLVILLLIAVRWGSHAVSENWQLRQAQRHGEQRLLDYISDVRRTLSRFYHL
PYLMTNEANTLKLFQGDDRPQAQLQQQLAQLDKAANTKGWYILTLSGSLLTASKNAENWK
LSDGKAIIHKILQQREGISIVTKSVGSTPTYFVAAPVYLDVEIVGAVAVQVDLNVLADQW
FASDELILFQNSQRHYFLSSSSVYSADWIATHPEVVAAAQKRSLFDGTRLTLWQVEQAPY
LAQSVTLDDLNWTLTYLTPLKNLNATVNWISTSAMVGVLLLLLLMRLRYEQYQKRLSEAK
IQHVLFEAEERQRNMINKTHVGLLLIDGQGRIEEINPMAKRYFSLSDSMVRQLQAWSLFD
TGNPNATVPLLLKNLTEHQELADITNVETVARRSDGSLFPVLFSLIAVSWKDRRHYLVTL
IDISKRKKAEIALQNANRDLQQRVEERTAALKSAQQELIEASKMAALGRMSSAITHELNQ
PLTGLRTLLSSNELLLERGETQLLKANTKLVHSLIDRMAAMTSQLKSFAFNRPDALQAIS
LPDALQEILRIHQARLTPVDVRVRLSSDLPLVMGEEQRLRQVLGNLVSNALDAMSQTLEP
KLSISAVSEEDQVIVRVSDNGCGIAPELLTTMFEPFQTSKKMGEGLGLGLAIVANSLRDM
QGSIVATNNPDAGMSFEIRLRAAQ