Protein Info for CSW01_14700 in Vibrio cholerae E7946 ATCC 55056

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 452 transmembrane" amino acids 26 to 44 (19 residues), see Phobius details amino acids 64 to 82 (19 residues), see Phobius details amino acids 94 to 115 (22 residues), see Phobius details amino acids 120 to 140 (21 residues), see Phobius details amino acids 160 to 183 (24 residues), see Phobius details amino acids 189 to 209 (21 residues), see Phobius details amino acids 255 to 274 (20 residues), see Phobius details amino acids 294 to 313 (20 residues), see Phobius details amino acids 325 to 342 (18 residues), see Phobius details amino acids 354 to 374 (21 residues), see Phobius details amino acids 385 to 405 (21 residues), see Phobius details amino acids 417 to 437 (21 residues), see Phobius details TIGR00712: glycerol-3-phosphate transporter" amino acids 1 to 439 (439 residues), 792 bits, see alignment E=1.8e-242 PF07690: MFS_1" amino acids 34 to 401 (368 residues), 189.5 bits, see alignment E=8.2e-60 TIGR00881: phosphoglycerate transporter family protein" amino acids 35 to 418 (384 residues), 507.9 bits, see alignment E=1.7e-156

Best Hits

Swiss-Prot: 71% identical to GLPT_ECOLI: Glycerol-3-phosphate transporter (glpT) from Escherichia coli (strain K12)

KEGG orthology group: K02445, MFS transporter, OPA family, glycerol-3-phosphate transporter (inferred from 100% identity to vch:VCA0137)

MetaCyc: 71% identical to sn-glycerol 3-phosphate:phosphate antiporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-22

Predicted SEED Role

"Glycerol-3-phosphate transporter" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (452 amino acids)

>CSW01_14700 MFS transporter (Vibrio cholerae E7946 ATCC 55056)
MFELFKPAAHTQRLPSDKVDSVYSRLRWQLFIGIFVGYAGYYLVRKNFSLAMPYLIEQGF
SRGDLGVALGAVSIAYGLSKFLMGNVSDRSNPRYFLSAGLLLSALVMFCFGFMPWATGSI
TAMFILLFLNGWFQGMGWPACGRTMVHWWSRKERGEIVSVWNVAHNVGGGLIGPIFLLGL
WMFNDDWRTAFYVPAFFAVLVAVFTWLVMRDTPQSCGLPPIEEYKNDYPDDYDKSHENEM
TAKEIFFKYVFNNKLLWSIAIANAFVYLIRYGVLDWAPVYLKEAKHFTVDKSSWAYFLYE
WAGIPGTLLCGWISDKVFKGRRAPAGILFMVLVTLAVLVYWFNPAGNPAVDMAALVAIGF
LIYGPVMLIGLYALELAPKKAAGTAAGLTGLFGYLGGAVAANAILGYTVDHFGWDGGFMV
LVASCVLSVLCLIYAFVGERAHHNDKLKQATI