Protein Info for CSW01_14660 in Vibrio cholerae E7946 ATCC 55056

Annotation: ribose ABC transporter substrate-binding protein RbsB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 294 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF00532: Peripla_BP_1" amino acids 27 to 277 (251 residues), 89.7 bits, see alignment E=4.7e-29 PF13407: Peripla_BP_4" amino acids 29 to 280 (252 residues), 205.9 bits, see alignment E=1.7e-64 PF13377: Peripla_BP_3" amino acids 157 to 282 (126 residues), 42.2 bits, see alignment E=2e-14

Best Hits

Swiss-Prot: 71% identical to RBSB_HAEIN: Ribose import binding protein RbsB (rbsB) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K10439, ribose transport system substrate-binding protein (inferred from 100% identity to vch:VCA0130)

MetaCyc: 70% identical to ribose ABC transporter periplasmic binding protein (Escherichia coli K-12 substr. MG1655)
ABC-28-RXN

Predicted SEED Role

"Ribose ABC transport system, periplasmic ribose-binding protein RbsB (TC 3.A.1.2.1)" in subsystem D-ribose utilization (TC 3.A.1.2.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (294 amino acids)

>CSW01_14660 ribose ABC transporter substrate-binding protein RbsB (Vibrio cholerae E7946 ATCC 55056)
MRMKKLTTLISAALLSTSVSFVAQAQDTVAIVLSTLNNPFFVTMKDGAEAKAKELGYNLI
VLDSQNDPSKELSNVEDLTVRGVKAILINPTDSDAVSNAIRIANRSKIPVLTLDRGASRG
EVVSHIASDNVVGGEMAGHFIEAKIGSDAKVIQLEGIAGTSAARERGEGFMNAVKGSKMQ
LLASQPADFDRTKGLNVMENLLAANPDVQAVFAQNDEMALGALRAIQASGKSVMIVGFDG
TDDGIAAVERGQLAATVAQQPDMIGAIGIETADKMLKGEKVEAYIPVALKVIAK