Protein Info for CSW01_14270 in Vibrio cholerae E7946 ATCC 55056

Annotation: protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1084 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF07676: PD40" amino acids 78 to 101 (24 residues), 21.1 bits, see alignment (E = 6e-08) amino acids 116 to 143 (28 residues), 15.5 bits, see alignment (E = 3.5e-06) amino acids 227 to 262 (36 residues), 33.5 bits, see alignment (E = 7.8e-12) amino acids 366 to 401 (36 residues), 33.5 bits, see alignment (E = 7.6e-12) PF14684: Tricorn_C1" amino acids 708 to 774 (67 residues), 88.1 bits, see alignment 7.8e-29 PF03572: Peptidase_S41" amino acids 899 to 1055 (157 residues), 89 bits, see alignment E=6.6e-29

Best Hits

KEGG orthology group: K08676, tricorn protease [EC: 3.4.21.-] (inferred from 100% identity to vco:VC0395_0089)

Predicted SEED Role

"Protease-related protein"

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1084 amino acids)

>CSW01_14270 protease (Vibrio cholerae E7946 ATCC 55056)
MHLPHFALSSVLSLTLCAIPNLGFASSNQTEDSTQARPTWLRDIALSPDGQKIAFTYAGQ
IWLVPAQGGDAVALTESGVYSETPIWSPDSQSIAFTADRYGLGDVFILSIQGGESRRLTY
HGAKDIPYAFSADGQQLYFSSRRLGDDKANANVKQGSFMAQLYSVPAAGGREQRVLPIAI
SDLAISPSHSDILYTNQPSDEQPWRKGALSDATRDIWQWSPLTGKHTQITTFRGEDRNPV
WSADGSSMYYLSEQAGSFNVWQQRFDGSEPVQITDHQKLPVRFLSASLQGDLAYGFDGEI
WRLKAGAKQAEKVPVSIRRSAMPDGRHNVNFNLEATEMVVAPNAAEVAIVARGDVYVVSL
LSGLTQRITDTPEAERDVSFSSDGYRLIYASEREGSWNLYQSYVNDGGKSFSSSLDIIEE
PVLTTEQDVIQPLYSPNLKRIVYRENRNTLKVYDIEQDKTYTLLDAHALYSYFDKDLSYQ
WSPDSEYIVTRDRAMSNGDIQLLKFDGSEAPINLSQSGFSEFAPQFSADGQWVYWLTDAK
GLRDIDDMVVQYDVYGVALNREAKFNFNKTQEQLWLEEEIAAEKNLGPGQNPPAELTVVE
NKGLKQRTMRMTPTSLNIIFKHLTHDNQALIIAYQLGDSVQISEINLRSGEMTALFNRLS
EDAALLAMASDDASLLIMGEHGIENLNVLTGESKFVRYEAKANFDFRAEIAYLFDHVWRL
TQTKFYDPQMHGVDWQQYGDLYRKHLPSIRTYSDFAELLSEMVGDLNVSHTGAFFMAGNS
SWEEPASLGLYYDDRYRGKGVRVKSLLPGGPADTYQSPIKAGAIIYSVNGKEISDQQDIY
PFLNFTQGKLTRLSVLVPGEEKAQNFTLVPITLEEESELLYEQWVEQRRALVETLSDGRL
GYVHLAAMDAASFEQMQNDMFGLEKDKLGLVVDVRFNAGGWLHDQVMEILSGTRHSVMQT
RDGYVVSSFPERRWAKPSIMLANADSYSDGSIVPYFYQKEGLGKLVGERVPGTGTAVIWE
QQQEPGLIYGVPQLGIKDEQGRWFENQEIIPDILVYNDPESVVAGEDRQLAAAVEALLLE
ISSK