Protein Info for CSW01_14140 in Vibrio cholerae E7946 ATCC 55056

Annotation: type VI secretion system tip protein VgrG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 694 TIGR03361: type VI secretion system Vgr family protein" amino acids 10 to 526 (517 residues), 621.5 bits, see alignment E=1.1e-190 TIGR01646: Rhs element Vgr protein" amino acids 21 to 508 (488 residues), 435.8 bits, see alignment E=2.4e-134 PF05954: Phage_GPD" amino acids 42 to 334 (293 residues), 270.1 bits, see alignment E=2.4e-84 PF04717: Phage_base_V" amino acids 392 to 458 (67 residues), 51.8 bits, see alignment E=8.4e-18

Best Hits

KEGG orthology group: K11904, type VI secretion system secreted protein VgrG (inferred from 100% identity to vcj:VCD_000215)

Predicted SEED Role

"VgrG-3 protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (694 amino acids)

>CSW01_14140 type VI secretion system tip protein VgrG (Vibrio cholerae E7946 ATCC 55056)
MATLAYSIEVEGLEDETLVVRGFHGQESLSNSVFLGQACYGFRYQMQLASRVSNLTADQM
VDKRAELKLYRNSQLVQRVHGIVRAFSQGDIGHHHTFYQLTLVPALERLSLRHNSRIFQK
QTVPEILSILLQEMGIHDYAFALKRDCVQREFCVQYRESDIDFLHRLAAEEGLVYSFVHE
AGKHTLYFSDASDSLSKLPEPIPYNALAGGTMDTPYIHGLTYRTQAEVSEVQLKDYSFKK
PAYSFLQTVQGTELDYQQTRYQHFDAPGRYKDDVNGAAFSQIRLDYLRRHAHTATGQSNE
PLLRAGYKFDLQEHLDPAMNRDWVVVSINHQGEQPQALQEEGGSGATTYNNQFSLIPGHL
HWRAEPQPKPQVDGPMIATVVGPEGEEIFCDEHGRVKIHFPWDRYSNGNEQSSCWVRVSQ
GWAGSQYGFIAIPRIGHEVIVSFLNGDPDQPIITGRTYHATNTPPYTLPEHKTKTVLRTE
THQGEGFNELSFEDQAGKEQIYLHAQKDFDGLIENDHTTVIRHDQHLTVENDQFTQIKHN
QHLTVEGESRTLVKLDCSSEIGGSLQQKIGSKAIYDAGTEVHLKAGNKLVLEAGNELTIK
AGGSFIKVDAGGVHVVGSAINLNSGGSAGSGSGYGGKMAELPQGVDKAKTPQEIELAAVT
PTQQSMSPLLKARQIEALKGPAPVCEVCEEAKGN