Protein Info for CSW01_14005 in Vibrio cholerae E7946 ATCC 55056

Annotation: ATP synthase subunit gamma

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 288 TIGR01146: ATP synthase F1, gamma subunit" amino acids 1 to 288 (288 residues), 367.1 bits, see alignment E=4.4e-114 PF00231: ATP-synt" amino acids 4 to 288 (285 residues), 353.3 bits, see alignment E=6.7e-110

Best Hits

Swiss-Prot: 100% identical to ATPG_VIBCH: ATP synthase gamma chain (atpG) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K02115, F-type H+-transporting ATPase subunit gamma [EC: 3.6.3.14] (inferred from 100% identity to vch:VC2765)

MetaCyc: 70% identical to ATP synthase F1 complex subunit gamma (Escherichia coli K-12 substr. MG1655)
ATPSYN-RXN [EC: 7.1.2.2]; RXN0-7041 [EC: 7.1.2.2]

Predicted SEED Role

"ATP synthase gamma chain (EC 3.6.3.14)" in subsystem F0F1-type ATP synthase (EC 3.6.3.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.14

Use Curated BLAST to search for 3.6.3.14 or 7.1.2.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (288 amino acids)

>CSW01_14005 ATP synthase subunit gamma (Vibrio cholerae E7946 ATCC 55056)
MAGAKEIRTKIGSVKSTQKITKAMEMVAASKMRRSQDAMESSRPYAQTIRKVIGHVANAS
LEYRHPYLEEREAKRVGYIIISTDRGLCGGLNINLFKKAITDMQTWKEKGAQIELAIIGS
KATAFFNNSGAKVAAQVSGLGDSPSLEDLIGSVGVMLKKYDKGELDRLYLVFNQFVNTMV
QKPKIDQLLPLPKSDSEDMQRDHMWDYIYEPEPKPLLDALLLRFIESQVYQGVVENLACE
QAARMVAMKAATDNASNLIDDLQLVYNKARQAAITQELSEIVGGAAAV