Protein Info for CSW01_13840 in Vibrio cholerae E7946 ATCC 55056

Annotation: translational GTPase TypA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 609 TIGR00231: small GTP-binding protein domain" amino acids 8 to 155 (148 residues), 82.6 bits, see alignment E=2.6e-27 PF00009: GTP_EFTU" amino acids 8 to 198 (191 residues), 197.9 bits, see alignment E=3e-62 TIGR01394: GTP-binding protein TypA/BipA" amino acids 9 to 603 (595 residues), 981.6 bits, see alignment E=1.2e-299 PF01926: MMR_HSR1" amino acids 12 to 133 (122 residues), 26.1 bits, see alignment E=2e-09 PF03144: GTP_EFTU_D2" amino acids 223 to 293 (71 residues), 44.3 bits, see alignment E=5e-15 PF00679: EFG_C" amino acids 399 to 481 (83 residues), 79.3 bits, see alignment E=4.5e-26 PF21018: BipA_C" amino acids 489 to 597 (109 residues), 153.9 bits, see alignment E=3e-49

Best Hits

Swiss-Prot: 77% identical to TYPA_ECOLI: GTP-binding protein TypA/BipA (typA) from Escherichia coli (strain K12)

KEGG orthology group: K06207, GTP-binding protein (inferred from 100% identity to vcm:VCM66_2664)

Predicted SEED Role

"GTP-binding protein TypA/BipA" in subsystem Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (609 amino acids)

>CSW01_13840 translational GTPase TypA (Vibrio cholerae E7946 ATCC 55056)
MTTPQIEKLRNIAIIAHVDHGKTTLVDKLLQQSGTLESRGDVEERVMDSNDIEKERGITI
LAKNTAINWNDYRINIVDTPGHADFGGEVERIMSMVDSVLLIVDAVDGPMPQTRFVTQKA
FAHGLKPIVVINKIDRPGARPDWVMDQVFDLFDNLGATDEQLDFQVVYASALNGWATLVE
GETGENMEPLFQAIVDNVAAPQVDLDGPLQMQISQLDYSSYVGVIGVGRIKRGKVKPNQQ
VTVIGADGKKRNGKIGTVLGYLGLQRSETDQATAGDIVAVTGLGELKISDTICDVNALEA
LPPLSVDEPTVTMTFQVNTSPFAGKEGKFVTSRNILERLEKELVHNVALRVEQTEDPDKF
RVSGRGELHLSILIENMRREGFELAVSRPEVILKHEDGQLMEPFETVTIDVQEEHQGGIM
EKIGMRKGELKDMSPDGKGRIRMDFVMPSRGLIGFQTEFMTLTSGSGLLYHSFDHYGPHK
GGVIGQRVNGVLVSNGTGKALTNALFNLQERGRMFIGHGVEVYEGMVIGIHSRDNDLTVN
PLKGKQLTNVRASGTDDAQVLTPPIIMSLEQALEFIDDDELVEVTPVSIRIRKRFLTEND
RKRASRDAK