Protein Info for CSW01_13765 in Vibrio cholerae E7946 ATCC 55056

Annotation: type II secretion system protein GspI

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 117 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF07963: N_methyl" amino acids 1 to 26 (26 residues), 34.3 bits, see alignment 1.2e-12 TIGR02532: prepilin-type N-terminal cleavage/methylation domain" amino acids 4 to 24 (21 residues), 29.8 bits, see alignment 3.7e-11 TIGR01707: type II secretion system protein I" amino acids 6 to 103 (98 residues), 143.9 bits, see alignment E=2e-46 PF02501: T2SSI" amino acids 40 to 116 (77 residues), 80.9 bits, see alignment E=5.9e-27

Best Hits

Swiss-Prot: 100% identical to GSPI_VIBCH: Type II secretion system protein I (epsI) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K02458, general secretion pathway protein I (inferred from 100% identity to vco:VC0395_A2301)

Predicted SEED Role

"General secretion pathway protein I"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (117 amino acids)

>CSW01_13765 type II secretion system protein GspI (Vibrio cholerae E7946 ATCC 55056)
MKSKRGFTLLEVLVALAIFATAAISVIRSVSQHINTVNYLEEKMFAAMVVDNQMAQVMLN
PQSLAAREGSEQMAGRTWYWKLSPVKTADNLLKAFDVSVATEKGATPVVTVRSYVAN