Protein Info for CSW01_13295 in Vibrio cholerae E7946 ATCC 55056

Annotation: cell division protein DamX

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 491 transmembrane" amino acids 232 to 254 (23 residues), see Phobius details PF13401: AAA_22" amino acids 26 to 153 (128 residues), 50.4 bits, see alignment E=4.4e-17 PF05036: SPOR" amino acids 404 to 477 (74 residues), 38.2 bits, see alignment E=2.3e-13

Best Hits

KEGG orthology group: K03112, DamX protein (inferred from 100% identity to vcj:VCD_001736)

Predicted SEED Role

"DamX, an inner membrane protein involved in bile resistance"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (491 amino acids)

>CSW01_13295 cell division protein DamX (Vibrio cholerae E7946 ATCC 55056)
MSLAHELDLESQTELLERLQLLTRFGSNLVNVCGRQGAGKSWLAQRFLDSWAQDKNQSLL
MCHPNQSDEQRRVTMLSQLFSEPLYNSKDALAESFARLFEDQNCDIVIVVDDAHLLSESL
VSELWMLVLEAQTNPRWNVNVVLFAQDNGLDALLTRLSYGQEHKPVDLEIEMLSEDEADR
LFENRVMRYVDPQVERKVRNAYKKINPLPGEIMALAETKNEKRVVIRSIVGSPFNIALVV
LLLLLLLGGGYWWLLSKPVPQEGSLLEGEVAEQTAIPTLNSEANPLAQDGTSSANGDGIS
DAEGDNFGADDDTSALPPDVVDTTASVGIADDGKRVVINSDVVDALLQGKADTADTSAIN
NLVESTQAATELKTQTLEQTQVQNAQPKSVSFSFARDELKAMSPRSYTLQLAAMNSLQDV
QGFIDEHKLQGKVYVYPTLRNDVEWFIVTMGNYPTIQMARDASEKLSASLQALGPWAKSL
SQVQREIERKK