Protein Info for CSW01_13200 in Vibrio cholerae E7946 ATCC 55056

Annotation: glutathione-regulated potassium-efflux system ancillary protein KefG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 196 PF02525: Flavodoxin_2" amino acids 13 to 180 (168 residues), 167.2 bits, see alignment E=3.9e-53 PF03358: FMN_red" amino acids 57 to 121 (65 residues), 26 bits, see alignment E=6.3e-10

Best Hits

Swiss-Prot: 60% identical to KEFG_YERE8: Glutathione-regulated potassium-efflux system ancillary protein KefG (kefG) from Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)

KEGG orthology group: K11748, glutathione-regulated potassium-efflux system ancillary protein KefG (inferred from 100% identity to vcj:VCD_001756)

Predicted SEED Role

"Glutathione-regulated potassium-efflux system ancillary protein KefG" in subsystem Glutathione-regulated potassium-efflux system and associated functions or Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (196 amino acids)

>CSW01_13200 glutathione-regulated potassium-efflux system ancillary protein KefG (Vibrio cholerae E7946 ATCC 55056)
MRNLVNREQTKAKVLVVYAHPDPQHSVANQVMMEKIADLEHVSIIDLYATYPNFFIDVHA
EQQRLREHDVLVLQHPLYMYSCPALLKEWIDRVLSKGFAFGKQSELKGKLWRSVITTGGN
HTAYDQRGYNRYPLNEILQPFELSAALCQMHWIEPLVLYWSRNISDQERAQHAERYRQWL
QEIAHWQGEPYDATDQ