Protein Info for CSW01_13040 in Vibrio cholerae E7946 ATCC 55056

Annotation: protein translocase subunit SecY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 444 transmembrane" amino acids 21 to 42 (22 residues), see Phobius details amino acids 76 to 99 (24 residues), see Phobius details amino acids 121 to 140 (20 residues), see Phobius details amino acids 152 to 172 (21 residues), see Phobius details amino acids 181 to 201 (21 residues), see Phobius details amino acids 213 to 233 (21 residues), see Phobius details amino acids 269 to 292 (24 residues), see Phobius details amino acids 317 to 339 (23 residues), see Phobius details amino acids 374 to 394 (21 residues), see Phobius details amino acids 400 to 419 (20 residues), see Phobius details TIGR00967: preprotein translocase, SecY subunit" amino acids 20 to 430 (411 residues), 445.7 bits, see alignment E=7.8e-138 PF00344: SecY" amino acids 76 to 418 (343 residues), 396.4 bits, see alignment E=4.7e-123

Best Hits

Swiss-Prot: 100% identical to SECY_VIBCH: Protein translocase subunit SecY (secY) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K03076, preprotein translocase subunit SecY (inferred from 100% identity to vco:VC0395_A2154)

MetaCyc: 81% identical to Sec translocon subunit SecY (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Preprotein translocase secY subunit (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (444 amino acids)

>CSW01_13040 protein translocase subunit SecY (Vibrio cholerae E7946 ATCC 55056)
MARKPGQDFRSAQSGLSELKSRLFFVIGALLVFRAGSFVPIPGIDAAVLAELFEQQKGTI
VEMFNMFSGGALERASILALGIMPYISASIVVQLLTVVHPALAELKKEGEAGRRKISQYT
RYGTLVLATFQAIGIATGLPNMVNNLVVIDQTMFTLIATVSLVTGTMFLMWLGEQITERG
IGNGISILIFAGIVAGLPKAIGQTIEQARQGELHVLLLLLIAVLAFAVIYFVVFMERGQR
RIVVNYAKRQQGRKVFAAQSTHLPLKINMAGVIPAIFASSIILFPGTLAQWFGQNGESST
FGWLTDVSLALSPGQPLYVMLYAAAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPG
EQTAKYIDKVMTRLTLAGALYITFICLIPEFMMVAWNVRFYFGGTSLLIVVVVIMDFMAQ
VQTHLMSHQYESVLKKANLKGYGR