Protein Info for CSW01_12250 in Vibrio cholerae E7946 ATCC 55056

Annotation: site-specific tyrosine recombinase XerD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 302 PF13495: Phage_int_SAM_4" amino acids 11 to 94 (84 residues), 28 bits, see alignment E=3.5e-10 PF02899: Phage_int_SAM_1" amino acids 12 to 94 (83 residues), 67.8 bits, see alignment E=1.3e-22 TIGR02225: tyrosine recombinase XerD" amino acids 13 to 302 (290 residues), 387.9 bits, see alignment E=1.5e-120 PF00589: Phage_integrase" amino acids 116 to 289 (174 residues), 193.8 bits, see alignment E=3.2e-61

Best Hits

Swiss-Prot: 100% identical to XERD_VIBCH: Tyrosine recombinase XerD (xerD) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K04763, integrase/recombinase XerD (inferred from 100% identity to vco:VC0395_A1995)

Predicted SEED Role

"Tyrosine recombinase XerD"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (302 amino acids)

>CSW01_12250 site-specific tyrosine recombinase XerD (Vibrio cholerae E7946 ATCC 55056)
MSEALSPDQGLVEQFLDTMWFERGLAENTVASYRNDLSKLLEWMAQNQYRLDFISFAGLQ
EYQSWLSEQNYKPTSKARMLSAIRRLFQYLHREKVRADDPSALLVSPKLPTRLPKDLSEA
QVEALLSAPDPQSPLELRDKAMLELLYATGLRVTELVSLTMENMSLRQGVVRVMGKGGKE
RLVPMGENAIEWIETFLQQGRSLLLGEQTSDIVFPSSRGQQMTRQTFWHRIKHYAVIAGI
DVEKLSPHVLRHAFATHLLNYGADLRVVQMLLGHSDLSTTQIYTHVATERLKQLHNEHHP
RA