Protein Info for CSW01_12165 in Vibrio cholerae E7946 ATCC 55056

Annotation: cell division protein FtsW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 398 transmembrane" amino acids 27 to 49 (23 residues), see Phobius details amino acids 61 to 81 (21 residues), see Phobius details amino acids 90 to 110 (21 residues), see Phobius details amino acids 123 to 142 (20 residues), see Phobius details amino acids 154 to 172 (19 residues), see Phobius details amino acids 178 to 195 (18 residues), see Phobius details amino acids 202 to 222 (21 residues), see Phobius details amino acids 287 to 308 (22 residues), see Phobius details amino acids 320 to 344 (25 residues), see Phobius details amino acids 356 to 377 (22 residues), see Phobius details TIGR02614: cell division protein FtsW" amino acids 24 to 380 (357 residues), 433.1 bits, see alignment E=4.1e-134 PF01098: FTSW_RODA_SPOVE" amino acids 26 to 381 (356 residues), 392.6 bits, see alignment E=8.2e-122

Best Hits

Swiss-Prot: 85% identical to FTSW_VIBVY: Probable peptidoglycan glycosyltransferase FtsW (ftsW) from Vibrio vulnificus (strain YJ016)

KEGG orthology group: K03588, cell division protein FtsW (inferred from 100% identity to vch:VC2402)

MetaCyc: 61% identical to peptidoglycan glycosyltransferase FtsW (Escherichia coli K-12 substr. MG1655)
Peptidoglycan glycosyltransferase. [EC: 2.4.1.129]

Predicted SEED Role

"Cell division protein FtsW" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.129

Use Curated BLAST to search for 2.4.1.129

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (398 amino acids)

>CSW01_12165 cell division protein FtsW (Vibrio cholerae E7946 ATCC 55056)
MFLSGSFTKLSHWLRTSSPEALFDRQLVWIAFGLMLIGLVMVTSASFPISSRLTDQPFHF
MFRHAIFLLLAFLTSSMVLQVPLDRWMKYSSLLLGISFFLLIVVLVVGKSVNGASRWIPL
GLFNLQPAEVAKLSLFIFMSGYLVRKHDEVRQTFFGGFLKPIMVFGTLAVLLLGQPDLGT
VIVMLVTLFGMLFIAGAKLSQFLALMVAGVLAVVALIVAEPYRVRRVTSFLDPWEDPFGS
GYQLTQSLMAFGRGEWFGQGLGNSIQKLEYLPEAHTDFVFAVLAEELGFIGVVLVLVLIF
SLVLKAIFIGKKAFQHDQQFGGYLAFGIGIWFAFQTLVNVGAAAGMVPTKGLTLPLISYG
GSSLIIMSVAVSILLRIDHECRLADRHAPEEITVDEQE