Protein Info for CSW01_12015 in Vibrio cholerae E7946 ATCC 55056

Annotation: TIGR01212 family radical SAM protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 316 TIGR01212: radical SAM protein, TIGR01212 family" amino acids 10 to 304 (295 residues), 479.8 bits, see alignment E=1.5e-148 PF04055: Radical_SAM" amino acids 47 to 201 (155 residues), 73.6 bits, see alignment E=2.3e-24 PF16199: Radical_SAM_C" amino acids 213 to 295 (83 residues), 78.7 bits, see alignment E=2.9e-26

Best Hits

Swiss-Prot: 69% identical to YHCC_ECOLI: Protein YhcC (yhcC) from Escherichia coli (strain K12)

KEGG orthology group: K07139, (no description) (inferred from 100% identity to vcm:VCM66_2294)

Predicted SEED Role

"COG1242: Predicted Fe-S oxidoreductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (316 amino acids)

>CSW01_12015 TIGR01212 family radical SAM protein (Vibrio cholerae E7946 ATCC 55056)
MSEPMHLHQLVNTIGQDLQRRYGEKVHKLTLHGGFSCPNRDGTIGRGGCTFCNVASFADE
NTQQQSIQAQLKDRAGEIKRAKKYLAYFQAYTSTYAEVQVLKSMYEQALEEADIVGLCVG
TRPDCVPDAVLKLLADYVQQGYEIWLELGLQTAHDQTLKRINRGHDFACYAEITAKARAL
GIKVCTHLIVGLPGEERTENLTTLQQVLKVGTDGIKLHGLHIVEGSTMAKAWRAGRLTVL
DQDQYVSIACEMIRSTPPEIVYHRVSSAARRPTLLAPLWCENRWWAMTAIGQRLEKEGAQ
GSLLGTPFEYSPLNLK