Protein Info for CSW01_11785 in Vibrio cholerae E7946 ATCC 55056

Annotation: exonuclease V subunit gamma

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1148 TIGR01450: exodeoxyribonuclease V, gamma subunit" amino acids 2 to 1109 (1108 residues), 1553.7 bits, see alignment E=0 PF04257: Exonuc_V_gamma" amino acids 2 to 350 (349 residues), 385.8 bits, see alignment E=1.6e-119 PF17946: RecC_C" amino acids 839 to 1075 (237 residues), 183.4 bits, see alignment E=5e-58

Best Hits

KEGG orthology group: K03583, exodeoxyribonuclease V gamma subunit [EC: 3.1.11.5] (inferred from 100% identity to vch:VC2322)

Predicted SEED Role

"Exodeoxyribonuclease V gamma chain (EC 3.1.11.5)" in subsystem DNA-replication (EC 3.1.11.5)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.5

Use Curated BLAST to search for 3.1.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1148 amino acids)

>CSW01_11785 exonuclease V subunit gamma (Vibrio cholerae E7946 ATCC 55056)
MFTVYHSNQVETLKILLVHLIKNEPLDDPFIPESILVQSPGMSQWLKMALASELGVAANL
EFPLPATFIWQMFTQVLPDVPQRSAFNKEAMSWRLMELLPKLLDRTEFQPLQRYLQDDED
DSKRFQLAEKIADIFDGYLVYRPDWILSWEAGEDVVEIADQHPWQPILWRELYAYTHKQG
HSIYHRANLYQRFIEQLASGDFDRSTWPKRLFIFGISALPPRYIDALRAMGEHIDVHLML
TNPCQHYWGDIRDRKYLARVAAQKRKILQINGEQVTIGSEVSPLKGDVENYLQESMHLSH
AVGNSLLASMGKMGRDNLYLLAQNDQSELELFIEIQRDSLLHHIQADILHLQEHQDDAKF
ASSGHKPSIAAQDDSLQIALCHSPIREVEVLHDRLLAEFERDPSLKPRDVIVMVPDINAY
APYIQAVFGNAPGERFIPFSISDRSADQESPILTAFLQLLALPQSRCLASELLELLETPA
IMARFAIDEEEFATAKRWVEEAGIRWGLNSDTGAEFELPASEQNTWQFGIERMLLGYAMP
AEAGLYELGGQWLAPYNQVQGMSAELAGKLAHFVQTLSELRSQLAQTQSMEQWRYWLNEL
LERCFSVDLQGELALKTIRDSLVNLKQQLADAGYQQAVSPAIIRQVLTNKLSGTRISQRF
LAGQVNFCTLMPMRSIPFRRVCLLGMNDGVYPPNEMVEGFDLRNVQRRVGDRSRREESRY
LFLEALLSAKEQLYISYVGRSIQDNSERVPSVLVSELLEYCEQNYCLAGDENLESDDSGR
RLVEHLTTQYPMVPFSPQAFIAGSFAREWLPAARRQGQSSADFLTPLSDYLLEVSWPMEL
DLVELQRFWRLPVEYFFKRRLKVSFEPPLAVLEDDEPFALDGLSAYQLRDELVENLLACR
DGAERDQVVAQFAKQQRAQGKLPVAAFGDLELAQSAQQALALAEKIGFLCHQPLEDEEID
LRLQPFDDGREVLLRGWLVKRYQSGLVRARSGAIRSEDLLAAWIDHLCLAASGKAVTTHL
IGYERKEGVQHQMLPPLNDAQQAKTLLSELVALFCQGMNQPLAYFPKTALACVEAGFSRG
KWQEDEEKSYKKMADTFNDSFYIKGEGGNRYIARIWPQWSDELAKTLRQLAIKVLQTPRL
QVQDAEQV