Protein Info for CSW01_11780 in Vibrio cholerae E7946 ATCC 55056

Annotation: exodeoxyribonuclease V subunit beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1208 TIGR00609: exodeoxyribonuclease V, beta subunit" amino acids 12 to 1189 (1178 residues), 1183.9 bits, see alignment E=0 PF00580: UvrD-helicase" amino acids 19 to 438 (420 residues), 167.2 bits, see alignment E=1.6e-52 PF13245: AAA_19" amino acids 342 to 424 (83 residues), 25.3 bits, see alignment 3.6e-09 PF13361: UvrD_C" amino acids 442 to 813 (372 residues), 53.1 bits, see alignment E=8.7e-18 PF12705: PDDEXK_1" amino acids 966 to 1176 (211 residues), 25.9 bits, see alignment E=2.3e-09

Best Hits

KEGG orthology group: K03582, exodeoxyribonuclease V beta subunit [EC: 3.1.11.5] (inferred from 100% identity to vcj:VCD_002024)

Predicted SEED Role

"Exodeoxyribonuclease V beta chain (EC 3.1.11.5)" in subsystem DNA-replication (EC 3.1.11.5)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.5

Use Curated BLAST to search for 3.1.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1208 amino acids)

>CSW01_11780 exodeoxyribonuclease V subunit beta (Vibrio cholerae E7946 ATCC 55056)
MSADSNKLAVTLDTLRFPLHGARLIEASAGTGKTYTIAGLYLRLVLGHGCAETRHAHPLS
VDQILVVTFTEAATAELRDRIRRRLHDARLAFARGASDDPLLRSLLAEFTDHNLAVSLLL
SAERQMDEAAIFTIHGFCQRMLTQNAFESGSRFENEFVTDESRLKAQVVADYWRRQFYPL
PISLASEVRRLWPAPSALLAEIAGYLSGPPVKLTTPLMEGDLAALQQAQIARICEIKQHW
LVEREEIEPAVTGSDLHKNSQNALLRRLPILDAWAQSETHDLHVPSELEEFTQSGLLAKS
KKGNPPQLALFERIEAFLAEPVSLKTPLLVHAIHHCRHWLAKAKSTHHWLSFDDLLTQLS
AALDNDEQGLLGERIRTLYPVAMIDEFQDTDPLQYSIFSRLYLDYPQCGLLMIGDPKQAI
YAFRGADIFTYIKARNQVNAHYTLGTNWRSSAAMVAAVNQVFSSATHPFIYSDDIPFQPV
AASPGADKRHWSLEGQVQPALTYWWPEDLDKPQSKTDYYAQMAEACAAQIQHILTASASG
AATFHRGEAIEAGDLAVLVRTGNEARMVRDALSQQGIASVYLSNRDSVFASDVAQDIERL
LLAVWQPEDERLLRAAVASNLFALTASELDALNNDENEWEQLIAEFRQYRRLWSERGVLP
MLRAVLTQRHIAERWLAESEGERWLTDYLHISELLQQATREIDSDQGLLRFLTQAMADAA
QGLGGSDEQIQRLESERRLVQIVTIHKSKGLEYPLVFLPFVMSYRESSEGKYYDAESATT
WVDLTGNEEALAKADQERLAEDLRLLYVALTRAVYGCFIGIAPLRNGNSSQEPTSAHRSA
MGFLLQDGQEGGIADLQQALLKQCENLPDVVQCPPPKRFEQAYQPPQLDERELTARELSQ
AIDRRWRVTSYSGLVMQSSHARHDPLQELPLLEVGGFDLDSAQERDGAALESVERSIFNF
PRGARPGTFLHSLFEEVDFQQSAHSEPNTKIILELMESEQIESEWLPVLQQLVDTVLSTP
LDGKALRLQQIMAAQRLTELEFLLPIEVLDAPTLNRITQRHDPLSAHAGDLGFHAVQGML
KGFIDLVFQYQGRYYVLDWKSNHLGDDPAAYHPQRLGSAMAEHRYDLQYQIYALALHRFL
RSRLAHYNYEQHFGGVFYLFLRGMDGRGDQGVFHTKPSLALLDELDGLIAGRELAQRASK
AGQMELDL