Protein Info for CSW01_10810 in Vibrio cholerae E7946 ATCC 55056

Annotation: uracil permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 417 transmembrane" amino acids 7 to 25 (19 residues), see Phobius details amino acids 30 to 46 (17 residues), see Phobius details amino acids 53 to 72 (20 residues), see Phobius details amino acids 78 to 97 (20 residues), see Phobius details amino acids 107 to 128 (22 residues), see Phobius details amino acids 147 to 166 (20 residues), see Phobius details amino acids 173 to 197 (25 residues), see Phobius details amino acids 216 to 238 (23 residues), see Phobius details amino acids 295 to 316 (22 residues), see Phobius details amino acids 322 to 344 (23 residues), see Phobius details amino acids 356 to 373 (18 residues), see Phobius details amino acids 379 to 396 (18 residues), see Phobius details TIGR00801: uracil-xanthine permease" amino acids 3 to 395 (393 residues), 373 bits, see alignment E=1e-115 PF00860: Xan_ur_permease" amino acids 3 to 371 (369 residues), 316.5 bits, see alignment E=1.1e-98

Best Hits

KEGG orthology group: K02824, uracil permease (inferred from 100% identity to vcj:VCD_002206)

Predicted SEED Role

"Uracil permease" in subsystem De Novo Pyrimidine Synthesis or Pyrimidine utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (417 amino acids)

>CSW01_10810 uracil permease (Vibrio cholerae E7946 ATCC 55056)
MKNAIQGAQMLFVAFGALVLVPLLTGLDPNVALFGAGLGTLLFQLITRRSVPIFLASSFA
FIAPIMFGIQTWGIPATMGGLMAAGAVYIVLGGIIKVRGVAIIHKLLPPVVVGPVIMVIG
LGLAPAAVNMALGKTGDGSVQLVDPQAALWISCISLLVTVVFSVFAKGFFKLVPILAGIV
SGYAVSLVMGVVSFAAVEQAAWLALPNFTFPEFNINAILFMIPVAIAPAVEHVGDMLAIS
NVTNKDYLKKPGLHRTIAGDGVATMAATMLGAPPNTTYSEVTGAVMLTRAFNPAIMTWAA
ITAIVLALVGKLGALLQTIPVPVMGGIMILLFGSIATVGLNTLIKNQVDLHKSRNLVIVA
VTLVFGIGGMAFGVGDFSLQGVSLCGIVAIVLNLVLPNDLGENHVVDNAQMEEEARH