Protein Info for CSW01_10795 in Vibrio cholerae E7946 ATCC 55056

Annotation: NAD(P)H:quinone oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 186 PF03358: FMN_red" amino acids 9 to 133 (125 residues), 44.6 bits, see alignment E=5.6e-16

Best Hits

Swiss-Prot: 40% identical to NQOR_MARMS: NAD(P)H dehydrogenase (quinone) (Mmwyl1_4139) from Marinomonas sp. (strain MWYL1)

KEGG orthology group: K03809, Trp repressor binding protein (inferred from 100% identity to vcj:VCD_002209)

MetaCyc: 37% identical to NAD(P)H:quinone oxidoreductase (Escherichia coli K-12 substr. MG1655)
NAD(P)H dehydrogenase (quinone). [EC: 1.6.5.2]

Predicted SEED Role

"Flavoprotein WrbA"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.6.5.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (186 amino acids)

>CSW01_10795 NAD(P)H:quinone oxidoreductase (Vibrio cholerae E7946 ATCC 55056)
MISIVVLYYSRHGSTQALARQIARGVESVEGCQALLRTVAELDGTASNSDPYLSLDELKQ
CDGLALGSPVWFGNMAAPLKHFWDQTTPLWLSGALIDKPACVFTSSSTLHGGQETTQQSM
MLPLLHHGMLILGIPYSEPALHTTQSGGTPYGASHVHQQKTLSSEEAELARQLGKRLAHV
AKQLKG