Protein Info for CSW01_10395 in Vibrio cholerae E7946 ATCC 55056

Annotation: AraC family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1121 signal peptide" amino acids 7 to 11 (5 residues), see Phobius details transmembrane" amino acids 12 to 29 (18 residues), see Phobius details amino acids 734 to 758 (25 residues), see Phobius details PF12833: HTH_18" amino acids 1041 to 1116 (76 residues), 87.3 bits, see alignment 1.1e-28 PF00165: HTH_AraC" amino acids 1077 to 1116 (40 residues), 44.4 bits, see alignment (E = 2e-15)

Best Hits

KEGG orthology group: None (inferred from 100% identity to vcm:VCM66_2004)

Predicted SEED Role

"DNA-binding response regulator, AraC family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1121 amino acids)

>CSW01_10395 AraC family transcriptional regulator (Vibrio cholerae E7946 ATCC 55056)
MSLTGELVFRTLLYGCLLNILIPSLVLALDKSMSIFYPLPIQEQGKVIVAQNLYLGSDGG
IWVHDVHGKVMYFDGQNVLPRRGSVLPQLSSHIVYANSAFWAFEQHELFRTYPGGERELM
LSLTPGTQIIQMGASNGMIWMVDGENFYSYEIRSGRVESLSLHELYQLNSASKVVINDAQ
FLVSKWALATNVGVYLSDEQGFAHVKNSGKHFIQKLYFSHKRRELLVGSKRGALVIDIEN
KRPPLDRIGSSHVLSIAETEKEYWIGTEDGLFVYSFITGKIVQLESNNQDGYALLGKKIY
AMVNDFQGGMWIGTDKGIFYYSLFGQQFTRYPAQALSNDGSKTPIGKIAALNSDGDYLAI
TAQGLYNFNFSDELRKHLIYPGKVNDFVIAQEHLWIATEKGLVRYNLSRRSIDTPNLPLP
LLQTAIQHLSLDSDGNLWGTSDYQIWSYSLSEKNYRDYGSEWMVKAFSPSRITLLAAVKD
GIVIGTEHGAYSLLEKQIRFDFSSHRYGEILQVAEDSSGHIWLVGSYGVFQWRKDQPEAV
TVELIEENIQPLCIAESKQGMWLISTKGISYYRNQELTKHFGAPYGLISNEFLSASCAVG
EEQDNSSLIIGSQFGVVKTNTEELAVSNLPNIQVTFSQVSVNHTTKLLGYRMSEPLKIAY
GDSISFQFGALPSSRSQSLEYKLNDEQQWQRFDWALLNFDQLLPGKYRLKVRSANPTQRY
RTEALFDFEVLQPWYMTSIALVGYVLSVLGLLALALWWRTRMILAANRKLKAQVELKTSQ
LRHQSKIVLSNNHQLRKQLQLHHTILGNVLDNIDASLRHLSSYAKVRAWSEFEAPFNKVK
QELAQLHFMHRGDEDESKYHDLHLLIESALKSWQEEYSKALIKLTYSGEPRFVEVRQFNL
DVLFNAVLTDAIKRLYKHQELTIQLEVRNAQAVIVFSDFGAPIQNIDKTMVTLSGSSYPL
EELVIRSGGVLHVLALKERNVIELAWPLATLPELETIHKPEEGEQAAKVGIDEVEKEWLS
KVEKLIELHYSDPNFTTSTAAQALYVSERSLQRRFKAATGKTFKESLNEVRLEKACQSLL
SGAKIAQVAFDCGFNDPSYFSQRFKHHFGLSPSQFIEDQEN