Protein Info for CSW01_10325 in Vibrio cholerae E7946 ATCC 55056

Annotation: protein phosphatase CheZ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 239 PF04344: CheZ" amino acids 36 to 239 (204 residues), 260 bits, see alignment E=8.7e-82

Best Hits

Swiss-Prot: 100% identical to CHEZ_VIBC3: Protein phosphatase CheZ (cheZ) from Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)

KEGG orthology group: K03414, chemotaxis protein CheZ (inferred from 100% identity to vcj:VCD_002302)

Predicted SEED Role

"Chemotaxis response - phosphatase CheZ" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (239 amino acids)

>CSW01_10325 protein phosphatase CheZ (Vibrio cholerae E7946 ATCC 55056)
MISLEQAKELVQLLEQGRQDDANRLFTYVYESANNPMFKEIGMLTRDLHEALKNFQIDER
FSEIATDEIPDARERLHYVIQKTEVAANKTMDAVDRCMPIADKLHESLLLIRPEWNGLMN
GRIELMHFKSLCHRIDDLLSQVEGDSSELRGELTEILMAQDFQDLTGQIIKRVINLVNEV
EKRLVEILTVFGAAQKEQKADKATVASIEPEGPILNPHERIDAVSSQDEVDDLLSSLGF