Protein Info for CSW01_10055 in Vibrio cholerae E7946 ATCC 55056

Annotation: PTS glucose transporter subunit IIBC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 transmembrane" amino acids 40 to 63 (24 residues), see Phobius details amino acids 75 to 95 (21 residues), see Phobius details amino acids 103 to 125 (23 residues), see Phobius details amino acids 131 to 148 (18 residues), see Phobius details amino acids 167 to 188 (22 residues), see Phobius details amino acids 273 to 293 (21 residues), see Phobius details amino acids 302 to 319 (18 residues), see Phobius details amino acids 324 to 353 (30 residues), see Phobius details amino acids 376 to 399 (24 residues), see Phobius details amino acids 466 to 481 (16 residues), see Phobius details TIGR02002: PTS system, glucose-specific IIBC component" amino acids 26 to 497 (472 residues), 658.5 bits, see alignment E=6.9e-202 PF02378: PTS_EIIC" amino acids 37 to 342 (306 residues), 249.1 bits, see alignment E=6e-78 TIGR00826: PTS system, glucose-like IIB component" amino acids 400 to 482 (83 residues), 72 bits, see alignment E=4e-24 PF00367: PTS_EIIB" amino acids 426 to 458 (33 residues), 50.5 bits, see alignment (E = 1.1e-17)

Best Hits

KEGG orthology group: K02778, PTS system, glucose-specific IIB component [EC: 2.7.1.69] K02779, PTS system, glucose-specific IIC component (inferred from 100% identity to vcm:VCM66_1937)

Predicted SEED Role

"PTS system, glucose-specific IIB component (EC 2.7.1.69) / PTS system, glucose-specific IIC component (EC 2.7.1.69)" in subsystem Trehalose Uptake and Utilization (EC 2.7.1.69)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (500 amino acids)

>CSW01_10055 PTS glucose transporter subunit IIBC (Vibrio cholerae E7946 ATCC 55056)
MLTFRLRGYAVSPSNSNNLIRSINMFKNAFANLQKVGKALMLPVSVLPVAGILLGVGAAN
FSWLPEVVSHLMEQAGGSVFGQMPLLFAVGVALGFTNNDGVSGLSAIVGYGIMVATLKVM
ATVMGVSGIDTGVLGGILAGGVAAWSFNRFYKIQLPEYLGFFAGKRAVPIITGFISIALG
VVLSFIWPPIGSAIATFSDWAANQDPVTAFGIYGIVERSLIPFGLHHIWNVPFFYQAGTC
VNGAGETVNGIMTCFLTADDASRAAGNGFGQLAGGYLFKMFGLPAAAFAIAHCAKPENRA
KVMGIMASAALTSFLTGITEPIEFAFLFVAPVLYAIHAVLAGLAYVLTNALGVVHGHTFS
NGFIDFVVQSPRADNMLLLVGLGIGYAVLYYVVFTFVIRALNLKTPGREDESADKSASSG
NELAGDLVAAFGGKANITNLDACITRLRVSVADTALVDQDKLKKLGAAGVVMVSGGVQAI
FGTKSDNLKTEMDEWIRNNG