Protein Info for CSW01_09880 in Vibrio cholerae E7946 ATCC 55056

Annotation: deoxyguanosinetriphosphate triphosphohydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 TIGR01353: putative dGTPase" amino acids 24 to 436 (413 residues), 474.1 bits, see alignment E=2.4e-146 PF13286: HD_assoc" amino acids 343 to 433 (91 residues), 93.6 bits, see alignment E=9.3e-31

Best Hits

Swiss-Prot: 100% identical to DGT1A_VIBCH: Deoxyguanosinetriphosphate triphosphohydrolase-like protein 1 (VC_1979) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K01129, dGTPase [EC: 3.1.5.1] (inferred from 100% identity to vco:VC0395_A1566)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.5.1

Use Curated BLAST to search for 3.1.5.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (441 amino acids)

>CSW01_09880 deoxyguanosinetriphosphate triphosphohydrolase (Vibrio cholerae E7946 ATCC 55056)
MQVSLNPEWLARNNDEHKIRRNDHRSPFQRDRARILHSAAFRRLQAKTQVHGTSLNDFHR
TRLTHSLEAAQIGTGIVAQIKLKQPEFRELLPSDSLIDSLCLAHDIGHPPYGHGGEIALN
YMMRDHGGFEGNAQTFRIVTSLEPYTEHHGMNLSRRTLLGLLKYPALLSATRAAIPPPAV
AHQRQLKAKDWSPAKGIYDCDLASLDWVLEPLCESDRELLGQMRAEPSSPKEHRKTRFKS
LDCSIMELADDIAYGVHDLEDAIVLGMVTRAQWQEAAAAQLAECGDPWFEEHIAELSEML
FSGKHYVRKDAIGGIVNALLTSISVKPVEAPFHNELLAFNAYIEPHMGNALEVLKHFVSQ
YVIQIPQVQRFEYKGQQLIMDLFEALSADPERLLPQATGEKWRKAQEQDEGMRVICDYIA
AMTDAYAQRLHQQLFSAQSHY