Protein Info for CSW01_09620 in Vibrio cholerae E7946 ATCC 55056

Annotation: trigger factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 433 PF05697: Trigger_N" amino acids 1 to 144 (144 residues), 160.4 bits, see alignment E=5.5e-51 TIGR00115: trigger factor" amino acids 11 to 412 (402 residues), 475.9 bits, see alignment E=5.2e-147 PF00254: FKBP_C" amino acids 156 to 237 (82 residues), 58.5 bits, see alignment E=1e-19 PF05698: Trigger_C" amino acids 263 to 412 (150 residues), 140.9 bits, see alignment E=6.2e-45

Best Hits

Swiss-Prot: 100% identical to TIG_VIBCH: Trigger factor (tig) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K03545, trigger factor (inferred from 100% identity to vco:VC0395_A1513)

MetaCyc: 71% identical to trigger factor (Escherichia coli K-12 substr. MG1655)
Peptidylprolyl isomerase. [EC: 5.2.1.8]

Predicted SEED Role

"Cell division trigger factor (EC 5.2.1.8)" in subsystem Bacterial Cell Division (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (433 amino acids)

>CSW01_09620 trigger factor (Vibrio cholerae E7946 ATCC 55056)
MQVTVETLEGLQRRLNITVPAANIEDAVAAELRNIAKNRRFDGFRKGKVPMKMVAKMYGK
AVRQDVLGEVMQRHFIEAIVKEKINPAGAPTFAPVEIGEGKDLVFTATFEVYPEVELKGL
ENIAVEKPAAEVTDADVAEMLETLRKQQATWKEVDEAAENGKRVSIDFVGSIDGVEFEGG
KAENFPLEMGAGRMIPGFEDGIVGKTKGMEFVIDVTFPEDYHAENLKGKAAKFAIKVNKV
EARELPELNDEFVARFGVAEGGVDALKAEVRKNMERELKQAIKARIKEQAIEGLVKENEI
QVPSALIDQEINVLRQQAAQRFGGNVEAAAQLPRELFEEQAKRRVVVGLLLGEVIRTHEL
KADEEKVKALITEMATAYEDPSEVVSYYEQNQQLMNNMRNVALEEQAVDAIIAKAKVTEK
AISFSELMNPVAA