Protein Info for CSW01_09155 in Vibrio cholerae E7946 ATCC 55056

Annotation: PTS fructose transporter subunit IIC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 633 transmembrane" amino acids 291 to 312 (22 residues), see Phobius details amino acids 332 to 356 (25 residues), see Phobius details amino acids 376 to 402 (27 residues), see Phobius details amino acids 414 to 440 (27 residues), see Phobius details amino acids 449 to 472 (24 residues), see Phobius details amino acids 483 to 515 (33 residues), see Phobius details amino acids 535 to 552 (18 residues), see Phobius details amino acids 560 to 580 (21 residues), see Phobius details amino acids 598 to 620 (23 residues), see Phobius details TIGR00848: PTS system, fructose subfamily, IIA component" amino acids 5 to 131 (127 residues), 146.9 bits, see alignment E=4.3e-47 PF00359: PTS_EIIA_2" amino acids 5 to 147 (143 residues), 127.4 bits, see alignment E=6.6e-41 TIGR00829: PTS system, Fru family, IIB component" amino acids 165 to 247 (83 residues), 99.1 bits, see alignment E=2.1e-32 PF02302: PTS_IIB" amino acids 166 to 256 (91 residues), 62.5 bits, see alignment E=7.2e-21 TIGR01427: PTS system, Fru family, IIC component" amino acids 275 to 618 (344 residues), 282.2 bits, see alignment E=1.1e-87 PF02378: PTS_EIIC" amino acids 290 to 565 (276 residues), 62.4 bits, see alignment E=6e-21

Best Hits

KEGG orthology group: K02768, PTS system, fructose-specific IIA component [EC: 2.7.1.69] K02769, PTS system, fructose-specific IIB component [EC: 2.7.1.69] K02770, PTS system, fructose-specific IIC component (inferred from 100% identity to vco:VC0395_A1421)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (633 amino acids)

>CSW01_09155 PTS fructose transporter subunit IIC (Vibrio cholerae E7946 ATCC 55056)
MINQLINADLIQLDLQANSKQAVFEELINILHAQGRISDKAAFLKDIQAREELGNTGFED
GVAIPHAKSAAVTQPAVAIGVSREGIDYGAEDGLPSKLFFMIASPDGGDNHHIEVLAELS
SKLIEEGFIEAFLNTKNSEQALELLLKKSAPTPLANQAESKGLIIGVTGCPAGIAHTYLA
AEALEKGAAALGFEIKVETNGSIGVKNSPSAEEIERAEAIVVACDKQVDMARFAGKRLIK
TNVKAPIRDAQKLINEALRAPTYQAETVKAQSVANKASQARSDLYRFLMNGVSHMIPFVV
TGGLLIALALAVGGEPTEAGMAIPAGSMWNQILEVGVVAFTLMIPILAGYIAYAIADRPA
LSPGLIGGWIANNGSFYGADAGTGFIGAIIAGLLVGYFVKWITSINYHKFIQPLVPIMIA
PITASLFIAGLFIFVIGAPIASLMDGLTALLTSMSSGNVILLGIVLGGMAGFDMGGPFNK
VAFLFSVGMIASGQTQFMGAMACAIPVAPLGMALATAMGRKLELFESSELEAGKAAGAMG
LVGISEGAIPFAAQDPMSVIPANVLGSMVAAVMAFSFGITNSVAHGGPVVALLGAMNYPL
LALLCMAAGAGVTAITCVTLKKIRSQKFEAAAA