Protein Info for CSW01_09115 in Vibrio cholerae E7946 ATCC 55056

Annotation: sigma-54-dependent Fis family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 587 PF01590: GAF" amino acids 78 to 187 (110 residues), 46.7 bits, see alignment E=2.1e-15 PF00158: Sigma54_activat" amino acids 285 to 447 (163 residues), 205.5 bits, see alignment E=2.1e-64 PF14532: Sigma54_activ_2" amino acids 300 to 452 (153 residues), 53.6 bits, see alignment E=1.4e-17 PF07724: AAA_2" amino acids 302 to 422 (121 residues), 29.4 bits, see alignment E=3.5e-10 PF00004: AAA" amino acids 305 to 426 (122 residues), 22.7 bits, see alignment E=5.3e-08 PF07728: AAA_5" amino acids 305 to 424 (120 residues), 28.4 bits, see alignment E=6.8e-10 PF02954: HTH_8" amino acids 556 to 582 (27 residues), 35.3 bits, see alignment (E = 3.3e-12)

Best Hits

KEGG orthology group: None (inferred from 100% identity to vcm:VCM66_1740)

Predicted SEED Role

"Sigma-54 dependent transcriptional regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (587 amino acids)

>CSW01_09115 sigma-54-dependent Fis family transcriptional regulator (Vibrio cholerae E7946 ATCC 55056)
MMQLQQLSHVNWLVNSWQRSEQAGLTQQSRAQDIRLSDNKLKERRQELAGLIDTVSRFAL
PLFYQLFAHSDSRLILTDQHGVIIGSWGQARFREKLSQIALSSGACWQEPIKGTNAIGTA
LIEQKPISVIGEQHFIQHHHFISCSASPIFDYTGQLIGVLDITSEQQKHTLSTQVVVQNM
VQLVENQLLNQIPHGHVRIDLACEPSLLSSGWQGVIIADESGQILAHNQVAGQLLAQGRV
IGQSVEQVLPRPQTHASFIYTTTPLHSKQHRTRALTPASDLHFGDAEVERCWQQANRVID
KDIRLLILGQTGVGKNEFVKALHKNSQRKNGPLVAVNCGALAKELVEAELFGYVAGAFTG
ASHKGYQGKVRLADKGILFLDEIADLPLDAQSRLLHVLQDKTVLPVGSNHATKVDIQIIA
ATHKNLEQLVTQGLFRQDLYYRLSDLVVELPSFQQRQDRQALIHHIHRRYSDAGQQICGD
LMQRLLAYHWPGNLRELDSLIKVASLMAEGEGVLTFNHLPTHLAQKLSHAAPTATEDDQQ
KDIKSTVEASLLKTYQATQGNISQTSRLLGLSRNTIYRKLKALGILK