Protein Info for CSW01_08925 in Vibrio cholerae E7946 ATCC 55056

Annotation: sialic acid-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 321 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF03480: DctP" amino acids 28 to 307 (280 residues), 333.4 bits, see alignment E=6.1e-104 TIGR00787: TRAP transporter solute receptor, DctP family" amino acids 29 to 283 (255 residues), 254.4 bits, see alignment E=5.7e-80

Best Hits

Swiss-Prot: 100% identical to SIAP_VIBCH: Sialic acid-binding periplasmic protein SiaP (siaP) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: None (inferred from 100% identity to vch:VC1779)

Predicted SEED Role

"TRAP-type transport system, periplasmic component, predicted N-acetylneuraminate-binding protein" in subsystem Sialic Acid Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (321 amino acids)

>CSW01_08925 sialic acid-binding protein (Vibrio cholerae E7946 ATCC 55056)
MKTINKITIAILTLSAAASVNAATTLKMGMQASVGSVEYNSAKMLADTLEEMSQGEIKLA
LYPSAQLGDDRAMLQQLTLGDLDITYAEFGRMGLWIPRAEAVMLPYVAKDFDHLRRMFES
DFGQGVRDEMLQKFNWRALDTWYNGTRETTSNRPLNSIEDFKGLKLRVPNAKQNLNYAKL
SGASPTPMSFSEVYLALQTNAVDGQENPLPTIKTMKFYEVQKNLAMTHHIVNDQMVIISE
STWQKLSDTDKDIIQKAVQKVGDAHTQTVKTQEAELVSFFKSEGINVTYPDLEPFREAMQ
PLYKEFDSNIGQPIVSKLAAM