Protein Info for CSW01_08915 in Vibrio cholerae E7946 ATCC 55056

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 427 transmembrane" amino acids 6 to 32 (27 residues), see Phobius details amino acids 52 to 71 (20 residues), see Phobius details amino acids 92 to 113 (22 residues), see Phobius details amino acids 133 to 159 (27 residues), see Phobius details amino acids 166 to 190 (25 residues), see Phobius details amino acids 211 to 231 (21 residues), see Phobius details amino acids 240 to 260 (21 residues), see Phobius details amino acids 270 to 291 (22 residues), see Phobius details amino acids 303 to 325 (23 residues), see Phobius details amino acids 331 to 350 (20 residues), see Phobius details amino acids 356 to 379 (24 residues), see Phobius details amino acids 393 to 417 (25 residues), see Phobius details PF06808: DctM" amino acids 9 to 414 (406 residues), 399.5 bits, see alignment E=8.5e-124 TIGR00786: TRAP transporter, DctM subunit" amino acids 15 to 419 (405 residues), 464.9 bits, see alignment E=1e-143

Best Hits

Swiss-Prot: 100% identical to SIAM_VIBCH: Sialic acid TRAP transporter large permease protein SiaM (siaM) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: None (inferred from 100% identity to vch:VC1777)

Predicted SEED Role

"TRAP-type transport system, large permease component, predicted N-acetylneuraminate transporter" in subsystem Sialic Acid Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (427 amino acids)

>CSW01_08915 ABC transporter permease (Vibrio cholerae E7946 ATCC 55056)
MVGSIFGWLGLLFAGMPVGFSLIFVALAFLILTNSTGINFAAQQMLGGIDNFTLLAVPFF
VLTGHLMNSAGITERIFNFAKSLVGHITGSLGHVNIMASLLFSGMSGSALADAGGLGQLE
IKSMRDAKYHDDFAGGLTAASCIIGPLVPPSVPLVIYGVVSNTSIGALFLAGAIPGLLCC
IALMVMSYFICKKRGYMTLPKASRREQFKSLKEAFLSLLTPVIIIGGIFSGKFTPTEAAA
VSSLYALFLGTVVYNTLTLQGFIEILKETVNTTAVVALMVMGVTVFGWIVAREQLPQMLA
DYFLTISDNPLVLLLLINLLLLFLGTFIESLALLLLLVPFLVPVASAVGIDPVHFGVMAI
LNLMIGILTPPMGMALYVVSRVGDIPFHTLTRGVLPLLVPLFIVLALVAVFPQFTLLLPE
LFLGYGQ