Protein Info for CSW01_08895 in Vibrio cholerae E7946 ATCC 55056

Annotation: kelch domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 356 TIGR03547: mutatrotase, YjhT family" amino acids 8 to 356 (349 residues), 485.9 bits, see alignment E=3.4e-150 PF07646: Kelch_2" amino acids 61 to 109 (49 residues), 32 bits, see alignment 1.7e-11 PF13415: Kelch_3" amino acids 70 to 122 (53 residues), 25.5 bits, see alignment 2.3e-09

Best Hits

Swiss-Prot: 100% identical to Y1773_VIBCH: Kelch domain-containing protein VC_1773 (VC_1773) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: None (inferred from 100% identity to vcm:VCM66_1711)

Predicted SEED Role

"Sialic acid-induced transmembrane protein YjhT(NanM), possible mutarotase" in subsystem Sialic Acid Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (356 amino acids)

>CSW01_08895 kelch domain-containing protein (Vibrio cholerae E7946 ATCC 55056)
MAISFQLLPELPVGVKHGVGGIIGQKLYAGLGSSGNAFFVLDLKDMNSGWKSAADFPGIA
RNDAAYTVCGNKLYVFSGAGIEGNNSFPTVLMDGYVFDSQINQWKRLERTLPTGFLGASC
CSLSPTEIIFFGGYDKDTFNNFLSEISKIDVTKEPNKYKELITIFMSQPIDNYNWNKNVW
SFTPCNEHWSVVGENPFKPNCGSGIIHKNNVVTLIEGEVKPGLRSLETKRYLFKEGKLEY
SDSSASIIDICKNHEGLAGHFFGEIDNKIIVIGGAYFIGSQDAFIKGNLYAHNGLIKHFS
SNVWIFDGKSWENKCQLDAAGIAYGVSASNGKAMYVLGGENSNGDAMTRCLSLLMD