Protein Info for CSW01_08855 in Vibrio cholerae E7946 ATCC 55056

Annotation: type I restriction endonuclease subunit R

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1022 PF04313: HSDR_N" amino acids 133 to 228 (96 residues), 64.6 bits, see alignment E=3e-21 PF04851: ResIII" amino acids 292 to 487 (196 residues), 59.8 bits, see alignment E=8.1e-20 PF18766: SWI2_SNF2" amino acids 295 to 534 (240 residues), 88.3 bits, see alignment E=1.5e-28 PF00270: DEAD" amino acids 313 to 492 (180 residues), 36.5 bits, see alignment E=1.1e-12 PF22679: T1R_D3-like" amino acids 591 to 721 (131 residues), 63.1 bits, see alignment E=1.1e-20

Best Hits

Predicted SEED Role

"Type I restriction-modification system, restriction subunit R (EC 3.1.21.3)" in subsystem Restriction-Modification System (EC 3.1.21.3)

Isozymes

Compare fitness of predicted isozymes for: 3.1.21.3

Use Curated BLAST to search for 3.1.21.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1022 amino acids)

>CSW01_08855 type I restriction endonuclease subunit R (Vibrio cholerae E7946 ATCC 55056)
MVFMVSKTNEQALEAAIEKGLAGICKEELALGEAPLNYNNDLYLIGSPSDFDKQYALDTR
LFWQFLEDTQASELEKLKRTSPHDWQRKILERFDRMIKRHGVLRLLKKGLDVDDAFLSLM
YPAPLASSSEKVKKDFSANLFSVTRQVCYSNANPLEEIDMVLFINGIPLITLELKNPWTG
QNAVYHGQKQYRDDRDANQPLLNFARCLVHMAVDTDEVYMTTKLAGKNTFFLPFNKGFNF
GKGNPINPHGHKTAYLWQEVFRKESIANIIQHFIRLDGSSKKQLDKRTLFFPRYHQMDVV
RRLVDHCSVNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPISDDLPGSRGKEMPLFDS
VIVVTDRRLLDKQLRDNIKEFSEVKNIVAPAFKSSELKSALENGKKIIITTIQKFPYIVD
GIADLSDRRFAVIIDEAHSSQDGHNQDKLNEAMGFVSEDVLDKALQSAKNRKMRSNASYF
AFTATPKNTTLEKFGQRQADGTYVPFHLYSMKQAIEEGFILDVIANYTTYKSYYEIEKSI
QDNPEFDSKKAQKRLRAYVEASQETIDTKAEIMLEHFIKHVVNGKKLKGKGKGMVVTQNI
ESAIRYYRALTRQLNKMGNPFKVAIAFSGSKEVDGIEYTEADINGFPEGDTKDYFDVNYK
RKEPDSPIPKHVDQDAYRLLVVANKYLTGFDQPKLCAMYVDKKLASVLCVQALSRLNRSA
PKYGKKTEDLFVLDFFNSVDDIKTAFDPFYTSTTLSEATDVNVLHELKDDMDDTDVYEWF
EVEEFNKRFFEGREAQDLSPIIDIAAARFNHELELENEFKVDFKVKAKQFVKIYGQIASI
MPYEVVQWEKLFWFLKFLIPKLSVEDPDKEALDSLLDSVDLSSYGLQRVKLNHSIELDDS
ETELDPQNPNPRGAYGPEAEKDPLDEIIKIFNERWFQGWSATPEEQRVKFVNIAESIRNH
PDFEAKYQNNADPHTRELAFEKMLKEIMLQRRKDELELYKLFAQDPAFKASWTQSMQRMV
GM