Protein Info for CSW01_08360 in Vibrio cholerae E7946 ATCC 55056

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 382 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF13416: SBP_bac_8" amino acids 58 to 325 (268 residues), 74.3 bits, see alignment E=2.1e-24 PF01547: SBP_bac_1" amino acids 84 to 325 (242 residues), 33.4 bits, see alignment E=7.6e-12 PF13343: SBP_bac_6" amino acids 120 to 326 (207 residues), 42 bits, see alignment E=1.2e-14

Best Hits

Swiss-Prot: 46% identical to YNJB_ECOLI: Protein YnjB (ynjB) from Escherichia coli (strain K12)

KEGG orthology group: K05777, putative thiamine transport system substrate-binding protein (inferred from 100% identity to vch:VC1664)

Predicted SEED Role

"ABC transporter, periplasmic substrate-binding protein YnjB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (382 amino acids)

>CSW01_08360 ABC transporter substrate-binding protein (Vibrio cholerae E7946 ATCC 55056)
MKKMLTFLTTCALSFGVSAQSWEETTEKARGQTVYFHAWGGSQEINSYLRWSADLLKSRY
GVTLQHVKVTDIAETTTRLIAEKAAGKNEQGSVDLVWINGENFKSMKNNQLLYGPFVEDL
PNWPKVDKSLPVDSDFSEPTEGLEAPWGVGQLVFIHDKQQVNNPPASFAELLSYAQAFPN
RISYPQPPEFHGTSFLKAALIELTHYAPELNQAVEPATFEQLTQPLWQYLDELHAVAWRK
GKQFPAGSAQMMQLLDDGQLDLAITFNPNAVFSAQATGKLAPTAQSYAMKKGALTNIHFL
AIPWNANAKEGALVAINFLLSDEAQSRKGDLSIWGDPSILKPQFLTGSAKNTILFPAIAE
PHPSWQSALEAEWQKRYGNSLK