Protein Info for CSW01_08015 in Vibrio cholerae E7946 ATCC 55056
Annotation: ABC transporter substrate-binding protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K02030, polar amino acid transport system substrate-binding protein (inferred from 100% identity to vco:VC0395_A1200)Predicted SEED Role
"DinG family ATP-dependent helicase YoaA" in subsystem DNA repair, bacterial DinG and relatives
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (274 amino acids)
>CSW01_08015 ABC transporter substrate-binding protein (Vibrio cholerae E7946 ATCC 55056) MTVRSQLTHDSKTSLDHQGTVMLSNGYLKRYVRCCLLIIGLCPALLYAQSSPNAEDKLVR IASGEWPPFIGSDLPNYGFVGEIITQAFTKQGYQVEFQFLPWARAYAETQRGLYDATAIW MHSAEREIDFFYSLPVSQEEFVFFYPVKKPFDWKTLSDLAPYKLGGVLAYSYGKELDALL DSGVLTMERDGLAAKNLEKLAKGRVDLVPEEKHIGYYLINQQIPHLQDLITHHPTPFLTN SNYLLFPKQSARSQELLGVFNHYLVQTQKKKKKQ