Protein Info for CSW01_07775 in Vibrio cholerae E7946 ATCC 55056

Annotation: flagellar motor protein MotA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 267 to 289 (23 residues), see Phobius details amino acids 354 to 373 (20 residues), see Phobius details amino acids 392 to 413 (22 residues), see Phobius details PF01618: MotA_ExbB" amino acids 312 to 429 (118 residues), 103.2 bits, see alignment E=4.4e-34

Best Hits

KEGG orthology group: K03561, biopolymer transport protein ExbB (inferred from 100% identity to vcm:VCM66_1488)

Predicted SEED Role

"MotA/TolQ/ExbB proton channel family protein" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (457 amino acids)

>CSW01_07775 flagellar motor protein MotA (Vibrio cholerae E7946 ATCC 55056)
MTLKKTTLALALSLPFAFASVANASNSLVQQATQEKAQQQQHNLQREAGFVQTAQELQAA
KAELLAERNRLQKEADQLSSQFSDNENTLARLEETLRLETGSLGEMFGVVRQNAKELQSE
LDQSVTGVEPRAHQQSIDDVVAAKTLPSMAQLRGLWQAMSEEIRASGQVQTTEIQWLNGQ
GETQTVPALRLGSLGLISEQGYVKWDNARQQALSYQQLPSDFPTFSHIRTLVDGDVVTMK
VDPSRGVLLEQLALTPTLSQRLQAGGVIGNVILVLLGVGLIIALYRGAILATLRQKIKAQ
LKNPEQPGNNPLGRILAVYNKEQQRSVEALELRLLEAVVDEQNHLETGLSMLKLLAALAP
MLGLLGTVTGMIETFQVITQFGNGDPKVMAGGISMALVTTVEGLIAAIPLLLAHNILSAQ
AEAIRNILEKQGIGLVAQQAERDCGATVTQSRVEQAA