Protein Info for CSW01_07515 in Vibrio cholerae E7946 ATCC 55056

Annotation: tail-specific protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 665 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF08180: BAGE" amino acids 9 to 36 (28 residues), 36.7 bits, see alignment (E = 8.5e-13) PF17804: TSP_NTD" amino acids 50 to 233 (184 residues), 208.6 bits, see alignment E=2.5e-65 TIGR00225: C-terminal processing peptidase" amino acids 196 to 548 (353 residues), 370.3 bits, see alignment E=4.1e-115 PF00595: PDZ" amino acids 240 to 321 (82 residues), 42.2 bits, see alignment E=2.1e-14 PF03572: Peptidase_S41" amino acids 357 to 526 (170 residues), 166.5 bits, see alignment E=1e-52 PF11818: DUF3340" amino acids 532 to 663 (132 residues), 144 bits, see alignment E=1e-45

Best Hits

Swiss-Prot: 61% identical to PRC_SALTY: Tail-specific protease (prc) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K03797, carboxyl-terminal processing protease [EC: 3.4.21.102] (inferred from 100% identity to vcj:VCD_002878)

MetaCyc: 60% identical to tail-specific protease (Escherichia coli K-12 substr. MG1655)
C-terminal processing peptidase. [EC: 3.4.21.102]

Predicted SEED Role

"Tail-specific protease precursor (EC 3.4.21.102)" (EC 3.4.21.102)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.21.102

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (665 amino acids)

>CSW01_07515 tail-specific protease (Vibrio cholerae E7946 ATCC 55056)
MKCRSKISLIAASLWLAAFSAQALEAKLKPEDLPLLVPEAQHATAAKRVTSRFTRSHYKQ
FNLDDQFSQAMFERYLEMLDYSRNIFTQADIDSFKAWSLQLDDQLKAGDNQIAYDLYNLS
MEKRFERFQYALSLLDQEMTFDADESIELDRTKSPWPKDLKEINELWRQRVKYDALSLKL
AGKEWPEIKETLDKRYNNAIKRLTQTKSEDVFQTYMNAFAREVDPHTSYLSPRNAEQFQS
EMNLSLEGIGAVLQMTDDYTIIRSLVAGGPAALSKQLGEGDRIIGVGQEGEDVVDVVGWR
LDDVVQLIKGPKGSKVKLLVLPEGKDAKSHVVTIVRDKIRLEDRAVKSEVIEKAGKKIGV
LEVPSFYVGLAQDTEKLLAELKAKKVDGIIVDLRNNGGGALTEATALSGLFITSGPVVQV
RDSYGRVNVNSDTDGSISYSGPMTVLINRYSASASEIFAAAMQDYGRAIILGENSFGKGT
VQQHRSLNHIYDLFDKELGYVQYTIQKFYRIDGGSTQNKGVVPDIAYPTAIAPSETGESV
EDNALPWDSIDKAKYERLNNFNTIIASLEAKHQQRVANDLEFGFIEQDIAKYRAEKDDNL
LSLNEKVRKEESAKADEERLARINQRQKALGKSTYASLQDIPKDYEAPDAYLDESVNIML
DMISR