Protein Info for CSW01_07255 in Vibrio cholerae E7946 ATCC 55056

Annotation: HlyD family type I secretion periplasmic adaptor subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 467 transmembrane" amino acids 53 to 74 (22 residues), see Phobius details TIGR01843: type I secretion membrane fusion protein, HlyD family" amino acids 51 to 467 (417 residues), 464.3 bits, see alignment E=2e-143 PF00529: CusB_dom_1" amino acids 65 to 418 (354 residues), 37.9 bits, see alignment E=2e-13 PF16576: HlyD_D23" amino acids 256 to 392 (137 residues), 35.4 bits, see alignment E=1e-12 PF13437: HlyD_3" amino acids 319 to 434 (116 residues), 72.5 bits, see alignment E=6.4e-24

Best Hits

KEGG orthology group: K12532, RTX toxin transporter (inferred from 100% identity to vco:VC0395_A1057)

Predicted SEED Role

"RTX toxin transporter, determinant D"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (467 amino acids)

>CSW01_07255 HlyD family type I secretion periplasmic adaptor subunit (Vibrio cholerae E7946 ATCC 55056)
MAASARAQTRGSLRMNTIMKRFFGQKSPHQPTEHHYEFLPAHLALAQRPPSPFARVTALT
LSLGVLAALLWAYWGKLDVQATATGRLVVSGRSQVIQSYEQSRLLSIHVRDGQRVEKGAP
LLTLDTLGVNQDITRLVSQAEFQTNELIRYRTLLNDQLLTHDPMFTALPAEQQALIHENY
LSEKNEFDSTLASITAEMKVNRTSQAARQSDIHALLQLTENISQRLAARKKLNQVKVIGH
VEYLEQEKELLEAQRQVAQQRAELEVLKSQYESLEERLTGFKAQKQREWLEKRRQARLQL
ASLNQELSKVREREQLEIIRSPVDGTVQQLSVYTLGAVLQPAQNLMIIVPENRVQQAEVQ
ILNKDVGFVYPGQSVTVKVDAFPYTRYGTIDAELLSISRDSTTDEQLGLVFPAQIQLKTN
HIMIDGQTVELTPGMSVVAEIKTDKRRVIDYLLSPIQEYQAEALRER