Protein Info for CSW01_06910 in Vibrio cholerae E7946 ATCC 55056

Annotation: molecular chaperone DnaK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 948 PF00012: HSP70" amino acids 138 to 321 (184 residues), 54.4 bits, see alignment E=6.8e-19 PF12531: DUF3731" amino acids 698 to 945 (248 residues), 340.6 bits, see alignment E=7.5e-106

Best Hits

KEGG orthology group: None (inferred from 100% identity to vco:VC0395_A0986)

Predicted SEED Role

"Chaperone protein DnaK" in subsystem Heat shock dnaK gene cluster extended or Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (948 amino acids)

>CSW01_06910 molecular chaperone DnaK (Vibrio cholerae E7946 ATCC 55056)
MNTRYRMSSPRFLVGIDLGTTNTVVAFCELSDALEQAPIEIFPVDQLIGPGEVVRRPLLP
SFRYHPSHGQFTDSDLTLPWSSELVEGDLPQVIIGEWARDLGAKVEGRQVSSAKSWLSHP
NVDRTQPILPWAGASDVEKVSPIVASASYLNHIRQAWNHRHPLNPLEQQEVVITVPASFD
ETARKLTLEAARLAGLSNIMLLEEPQAVCYDWHHRHQTQANEILHASPLILVCDVGGGTT
DLSLIAAQFDAQAALQLNRIGVGDHLMLGGDNIDLALAHVAERRFNQNKKLSAAGLSKLI
QQTRQAKESLLSADAPEQMKITLLGSGSKLLGGTQSVALHRDEVHQIALDGFFPLTQRDV
LPEKRRSAVVEFGLPYASDPAVSKHIAEFLSHHQGVVPSDPNTEPNTVSTDLLPTALLLN
GGVFNSSLITQRLIALLSDWLGRPITLLDNPHPDWSVALGAVAYAKARRGAQLKIGGGAA
RSYFLHLQEKNKLGKALCLLAKGSEEGQEIRLTSRRFALTVGEPVRFNLLTSTHDHVTQE
QRVQNGALFTIDTDKFQPLPPYIVTLPALDPTELAANQKQRVEVQLACQLTEVGTLQIVC
VNPNDEKQRWQVEFDIRHSLTQAGELEDSVATSPKLQQAKDLISKIYSANKTSADQQAIK
TLTKELEKRLGKRETWDFSTLRSLFDTLALGRKRRRRSEPHEKNWLRLAGLCLRPGFGDA
TDGWRIEQIWALYQQGIQFTNTQGWTDWWVFWRRVAGGLNQEQQETLLADIAKYLHPGAM
RTPASTKEAQEKGYEAMVRLAASLEHLQVEDKTLLATWFLNKALNHTQYQQAHWWALGRL
AARTPFYGSLHTCLPKEQIQQWLPKLLEQDWQQEPMCAFATVMMCRKTGDRTRDISEEWR
TQVLDKLKQSRVADSWINLVSDVVELDEAETQRAFGESLPNGLILLAH