Protein Info for CSW01_06865 in Vibrio cholerae E7946 ATCC 55056

Annotation: Cof-type HAD-IIB family hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 273 PF00702: Hydrolase" amino acids 2 to 230 (229 residues), 37.8 bits, see alignment E=5.6e-13 PF05116: S6PP" amino acids 3 to 75 (73 residues), 21.4 bits, see alignment E=3.4e-08 amino acids 162 to 267 (106 residues), 33.4 bits, see alignment E=7.3e-12 TIGR01484: HAD hydrolase, family IIB" amino acids 4 to 235 (232 residues), 92.1 bits, see alignment E=5.5e-30 TIGR00099: Cof-like hydrolase" amino acids 4 to 262 (259 residues), 223.4 bits, see alignment E=3.8e-70 PF08282: Hydrolase_3" amino acids 5 to 262 (258 residues), 225.9 bits, see alignment E=1.5e-70

Best Hits

KEGG orthology group: K07024, (no description) (inferred from 100% identity to vco:VC0395_A0977)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (273 amino acids)

>CSW01_06865 Cof-type HAD-IIB family hydrolase (Vibrio cholerae E7946 ATCC 55056)
MYKLIALDMDGTLLNSQKQISPRTKQAIAQARQQGIQVVLASGRPLDGMRSKLEELHLTT
ENDYVLYYNGSMVANVGTGEIIHQQIIDGKAAKRVATLAQEFGLNTHAFSQIHGLITPKT
SQYTEVEASINGLNITEMDFAQLADDHPIIKAMIVGEPEKLTQAIAQLPAQWREEFTVVQ
SAPFFLEFLNTGSNKGIGVQAIAAHLGIQASEVICMGDAENDHHMLQYAGLGIAMANAME
ETKHIADHITLSNDHDGVAVAIERFALGCFSEA