Protein Info for CSW01_06850 in Vibrio cholerae E7946 ATCC 55056

Annotation: amino acid ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 401 transmembrane" amino acids 30 to 48 (19 residues), see Phobius details amino acids 60 to 80 (21 residues), see Phobius details amino acids 95 to 120 (26 residues), see Phobius details amino acids 141 to 159 (19 residues), see Phobius details amino acids 190 to 212 (23 residues), see Phobius details amino acids 224 to 243 (20 residues), see Phobius details amino acids 263 to 285 (23 residues), see Phobius details amino acids 316 to 331 (16 residues), see Phobius details amino acids 343 to 359 (17 residues), see Phobius details amino acids 370 to 392 (23 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 91 to 155 (65 residues), 59.8 bits, see alignment E=1.5e-20 PF00528: BPD_transp_1" amino acids 228 to 396 (169 residues), 48.8 bits, see alignment E=3.6e-17

Best Hits

Swiss-Prot: 53% identical to AAPQ_RHIL3: General L-amino acid transport system permease protein AapQ (aapQ) from Rhizobium leguminosarum bv. viciae (strain 3841)

KEGG orthology group: K09970, general L-amino acid transport system permease protein (inferred from 100% identity to vch:VC1361)

Predicted SEED Role

"Glutamate Aspartate transport system permease protein GltJ (TC 3.A.1.3.4)" (TC 3.A.1.3.4)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (401 amino acids)

>CSW01_06850 amino acid ABC transporter permease (Vibrio cholerae E7946 ATCC 55056)
MKPTNKATPETSDAHSKHTNLLYNPTFRSVVFQLLAVCVLAFFLYTIVNNALTNLESRGI
ATGFAFLEQTAGFGISQSLIPYDETYSYGRTFLVGLLNTALVSVLGILLATILGFLIGIA
RLSSNWLISRLAAVYIETFRNLPLLLQIFFWYFVVLQALPSARESMHLGEWFYLNIKGLY
LAKPIFESGSIWVLVALIAGIIACWVLSIWATNRQRLTGQQTPMGRYILLLCVTFPVLVY
FLLGQPITAEYPVLRGFNFQGGISVLPELAALLVALTIYTASFIAEIVRSGINAVSHGQT
EAAMSLGLTRTKTLKLVIIPQALRIIIPPLTSQYLNLTKNSSLAMAIGYPDLVSVFAGTT
LNQTGQAIEIISMTMLVYLTLSLLTSALMNLYNRKVALVER