Protein Info for CSW01_06700 in Vibrio cholerae E7946 ATCC 55056

Annotation: galactose/methyl galactoside ABC transporter permease MglC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 337 transmembrane" amino acids 17 to 39 (23 residues), see Phobius details amino acids 47 to 67 (21 residues), see Phobius details amino acids 75 to 92 (18 residues), see Phobius details amino acids 105 to 130 (26 residues), see Phobius details amino acids 135 to 154 (20 residues), see Phobius details amino acids 184 to 202 (19 residues), see Phobius details amino acids 230 to 249 (20 residues), see Phobius details amino acids 269 to 300 (32 residues), see Phobius details amino acids 312 to 331 (20 residues), see Phobius details PF02653: BPD_transp_2" amino acids 42 to 326 (285 residues), 163 bits, see alignment E=4.1e-52

Best Hits

Swiss-Prot: 80% identical to MGLC_ECOLI: Galactoside transport system permease protein MglC (mglC) from Escherichia coli (strain K12)

KEGG orthology group: K10541, methyl-galactoside transport system permease protein (inferred from 100% identity to vcj:VCD_003010)

MetaCyc: 80% identical to D-galactose/methyl-galactoside ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
ABC-18-RXN; TRANS-RXN0-541

Predicted SEED Role

"Galactose/methyl galactoside ABC transport system, permease protein MglC (TC 3.A.1.2.3)" in subsystem Lactose and Galactose Uptake and Utilization (TC 3.A.1.2.3)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (337 amino acids)

>CSW01_06700 galactose/methyl galactoside ABC transporter permease MglC (Vibrio cholerae E7946 ATCC 55056)
MTMDAVKSFAIKHLKEGAIYAVLFILLAIIVIQEPSFLSLRNLSNILTQSSVRVIIALGV
AGLIVTQGTDLSAGRQVGLAAVISATLLQSMDNVNKVFPSLGEIPILAVIISVCLIGAII
GLVNGVIVAYLKVTPFIATLGTMIIVYGINSLYYDSVGASPIAGFDERFTTFTQGFIRIG
DFRFSYITFYAIIAIIFMWVLWNKTVFGKNIFAVGGNPEAAKVSGVNVPLTLLKVYALSG
VFYAFGGMLEAGRIGSATNNLGFLYELDAIAACVVGGVSFAGGVGSIAGVVTGVLIFTVI
NYGMTYIGVSPYWQYIIKGSIIIFAVALDSMKYANKK