Protein Info for CSW01_06640 in Vibrio cholerae E7946 ATCC 55056

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 449 transmembrane" amino acids 59 to 78 (20 residues), see Phobius details PF00027: cNMP_binding" amino acids 20 to 98 (79 residues), 32.3 bits, see alignment E=1.2e-11 PF02518: HATPase_c" amino acids 329 to 437 (109 residues), 70.4 bits, see alignment E=2.6e-23 PF14501: HATPase_c_5" amino acids 333 to 432 (100 residues), 33.4 bits, see alignment E=5.5e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to vcj:VCD_003021)

Predicted SEED Role

"Sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (449 amino acids)

>CSW01_06640 histidine kinase (Vibrio cholerae E7946 ATCC 55056)
MSNLAAVIERYFNHADRCITLPAGSILLAQNGYNDRLYYLRSGHVSGYFAEKGERRIKVF
SAASGAFIGVHSFFSGLWTASSTVIADSEVELAWIDRDTPVQDVEQYGSLSTQFMPVIVA
ELSQRQRRATQEAVAKERALERLYSAEQMTTLGQLAAGIAHELNNAIGVVSSKTERLEAL
FMELLEEVHPEASQFFDFGLLFGQKVSSSEARERGAVFEKQYQLPKDIARELARAVPANE
LSAHWLKNPHLAIRYWQMGRDLHDLRLAAKHSVGIVKSVKQLGRADIRLDEEVDLNSTIN
RALALLQSDLRRVSVRMRPGSLPIIKGSQTEWVQVWINLIKNACDAMAQTTEPTIDIQTR
CSRQRLYVTVANNGPEIDEATRRKIFQPSFTTKKEGLSFGLGLGLAIVKRIVSGYGGTVA
VKSDQDKTIFRIKLPVEGYHGETEHHLRG