Protein Info for CSW01_06470 in Vibrio cholerae E7946 ATCC 55056

Annotation: dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 431 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF01522: Polysacc_deac_1" amino acids 27 to 137 (111 residues), 61.9 bits, see alignment E=6e-21 PF02839: CBM_5_12" amino acids 339 to 379 (41 residues), 48.7 bits, see alignment 6.2e-17 amino acids 387 to 428 (42 residues), 42.1 bits, see alignment 7.1e-15

Best Hits

Swiss-Prot: 81% identical to DEAA_VIBAL: Chitin disaccharide deacetylase (deaA) from Vibrio alginolyticus

KEGG orthology group: None (inferred from 100% identity to vcm:VCM66_1235)

MetaCyc: 100% identical to chitin oligosaccharide deacetylase (Vibrio cholerae O1 biovar El Tor str. N16961)
3.5.1.-

Predicted SEED Role

"Deacetylase DA1"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (431 amino acids)

>CSW01_06470 dehydrogenase (Vibrio cholerae E7946 ATCC 55056)
MDTKMKLKKLALFTAISLAISGHSFANSTPKGTIYLTFDDGPVNASVEVIKVLNQGGVKA
TFYFNAWHLDGIGDENEDRALEALKLALDSGHIVGNHSYDHMIHNCVEEFGPTSGADCNA
TGNHQIHSYQDPVRDAASFEQNLITLEKYLPTIRSYPNYKGYELARLPYTNGWRVTKHFQ
ADGLCATSDNLKPWEPGYVCDPANPSNSVKASIQVQNILANQGYQTHGWDVDWAPENWGI
PMPANSLTEAVPFLAYVDKALNSCSPTTIEPINSKTQEFPCGTPLHADKVIVLTHDFLFE
DGKRGMGATQNLPKLAEFIRIAKEAGYVFDTMDNYTPRWSVGKTYQAGEYVLYQGVVYKA
VISHTAQQDWAPSSTSSLWTNADPATNWTLNVSYEQGDIVNYKGKRYLVSVPHVSQQDWT
PDTQNTLFTAL