Protein Info for CSW01_06235 in Vibrio cholerae E7946 ATCC 55056

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 129 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 36 to 57 (22 residues), see Phobius details amino acids 69 to 88 (20 residues), see Phobius details amino acids 94 to 117 (24 residues), see Phobius details PF03788: LrgA" amino acids 25 to 116 (92 residues), 82.6 bits, see alignment E=8.2e-28

Best Hits

Swiss-Prot: 100% identical to Y1233_VIBCH: UPF0299 membrane protein VC_1233 (VC_1233) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K06518, holin-like protein (inferred from 100% identity to vch:VC1233)

Predicted SEED Role

"Antiholin-like protein LrgA" in subsystem Murein hydrolase regulation and cell death

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (129 amino acids)

>CSW01_06235 hypothetical protein (Vibrio cholerae E7946 ATCC 55056)
MLILLMIKKIAQYCVSMGLIFLCLLAGINLQTWLGIAIPGSIIGLLILFGLMASGLVPVE
WVKPSATLFIRYMILLFVPISVGLMVHFDTLLANLAPILASAIGGTLIVMVTLGLILDRM
LKKGKKSCG