Protein Info for CSW01_05960 in Vibrio cholerae E7946 ATCC 55056
Annotation: PHP domain-containing protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 57% identical to RNAAM_ECOLI: 5'-3' exoribonuclease (yciV) from Escherichia coli (strain K12)
KEGG orthology group: K07053, (no description) (inferred from 100% identity to vcj:VCD_003166)MetaCyc: 57% identical to RNase AM (Escherichia coli K-12 substr. MG1655)
RXN-16009 [EC: 3.1.3.97]; 3.1.13.- [EC: 3.1.3.97]; RXN-24047 [EC: 3.1.3.97]
Predicted SEED Role
"COG0613, Predicted metal-dependent phosphoesterases (PHP family)"
Isozymes
No predicted isozymesUse Curated BLAST to search for 3.1.3.97
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (290 amino acids)
>CSW01_05960 PHP domain-containing protein (Vibrio cholerae E7946 ATCC 55056) MRIDLHSHTTASDGRFTYQQLIDRAVSFEIDVLAITDHDTVAALADARAYIAQQQYPLQL VNGIEISTVWQNKDIHIVGLNIDPNSEALGQLIARQQQRRVERAELIAHRLQKATREGVL EEVQHIADGAPITRAHFAKWLVDNGYATNMQQVFKKYLTRDNPGYVPPNWCSMSEAVSAI HAAGGQAVLAHPGRYDLTAKWLKRLMTAFVEAGGDAMEVAQPQQSPQEKRTLGDYAMEYQ LLASQGSDFHYPSPWMELGRNLWLPAGVEPVWKDWGLSPSNRVERLDEEE