Protein Info for CSW01_05595 in Vibrio cholerae E7946 ATCC 55056

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 321 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF04392: ABC_sub_bind" amino acids 29 to 320 (292 residues), 434.7 bits, see alignment E=8.2e-135

Best Hits

KEGG orthology group: K01989, putative ABC transport system substrate-binding protein (inferred from 100% identity to vco:VC0395_A0619)

Predicted SEED Role

"ABC transporter substrate-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (321 amino acids)

>CSW01_05595 ABC transporter substrate-binding protein (Vibrio cholerae E7946 ATCC 55056)
MRAGKVIATAVLAGAALLSSQSIMAKTAKVAVSQIVEHPALDATRQGLLDGLKAKGYEEG
KNLEFDYKTAQGNPAIAVQIARQFVGENPDVLVGIATPTAQALVSATKTIPIVFTAVTDP
VGAKLVKQLEQPGKNVTGLSDLSPVEQHVELIKEILPNVKSIGVVYNPGEANAVSLMELL
KLSAAKHGIKLVEATALKSADVQSATQAIAEKSDVIYALIDNTVASAIEGMIVAANQAKT
PVFGAATSYVERGAIASLGFDYYQIGVQTADYVAAILEGKEPGSLDVQVAKGSDLVINKT
AAEQLGITIPEAVLARATSTK