Protein Info for CSW01_05075 in Vibrio cholerae E7946 ATCC 55056

Annotation: PTS N-acetylmuramic acid transporter subunit IIBC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 523 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 37 to 63 (27 residues), see Phobius details amino acids 70 to 88 (19 residues), see Phobius details amino acids 93 to 114 (22 residues), see Phobius details amino acids 132 to 155 (24 residues), see Phobius details amino acids 169 to 177 (9 residues), see Phobius details amino acids 281 to 305 (25 residues), see Phobius details amino acids 312 to 330 (19 residues), see Phobius details amino acids 335 to 358 (24 residues), see Phobius details amino acids 365 to 383 (19 residues), see Phobius details amino acids 389 to 409 (21 residues), see Phobius details TIGR01998: PTS system, N-acetylglucosamine-specific IIBC component" amino acids 3 to 509 (507 residues), 720.4 bits, see alignment E=9.4e-221 PF02378: PTS_EIIC" amino acids 11 to 353 (343 residues), 200.8 bits, see alignment E=3.1e-63 TIGR00826: PTS system, glucose-like IIB component" amino acids 411 to 498 (88 residues), 77.6 bits, see alignment E=7e-26 PF00367: PTS_EIIB" amino acids 441 to 473 (33 residues), 50.5 bits, see alignment (E = 1.1e-17)

Best Hits

KEGG orthology group: K02803, PTS system, N-acetylglucosamine-specific IIB component [EC: 2.7.1.69] K02804, PTS system, N-acetylglucosamine-specific IIC component (inferred from 100% identity to vcm:VCM66_0951)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (523 amino acids)

>CSW01_05075 PTS N-acetylmuramic acid transporter subunit IIBC (Vibrio cholerae E7946 ATCC 55056)
MNILGYAQKLGKALMLPIATLPVAALLLRLGQPDLLGIPFMAAAGDAIFSQLPLLFGLGI
AIGLSKDGSGAAGLAGAVAYFVLSATAKTIDASINMSFFGGIFAGIIAGHSYNAFHTTRL
PEWLAFFAGKRLVPIMAGLFALVAGALSGVIWPSIQGGLDALAHAVSTSGALGQFVYGTL
NRALIPVGLHHVLNSYFWFGMGTCQEILVSGAQAAGQALPALEKLCVDPALAKTLVVGQE
HTFAFKNAVTPEITAVVKEVTEVVKSGDLHRFFGGDKSAGVFMNGFFPVMMFGLPGAALA
MYLAAPAERRHQVGGALFSVAFCSFLTGITEPLEFMFVFLAPALYAMHAVFTGLSLVVAN
MFGTLHGFGFSAGLIDFLLNWGLATKPATLFVIGLAFFALYFFTFTFAIRAFNLKSPGRE
DEEVETETDSADASKGDLARQYLKALGGHENLTSIDACITRLRLTLKDRSVADEAVLKKL
GAKGVVKLGENNLQVILGPLAEIVAGEMKAISPKEDLSDVKLP