Protein Info for CSW01_04850 in Vibrio cholerae E7946 ATCC 55056

Annotation: septal ring lytic transglycosylase RlpA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 263 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF03330: DPBB_1" amino acids 77 to 166 (90 residues), 103.5 bits, see alignment E=6e-34 TIGR00413: rare lipoprotein A" amino acids 79 to 173 (95 residues), 155.9 bits, see alignment E=6.9e-50 PF05036: SPOR" amino acids 188 to 256 (69 residues), 36.7 bits, see alignment E=4.5e-13

Best Hits

Swiss-Prot: 100% identical to RLPA_VIBCH: Endolytic peptidoglycan transglycosylase RlpA (rlpA) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K03642, rare lipoprotein A (inferred from 100% identity to vcm:VCM66_0904)

Predicted SEED Role

"Rare lipoprotein A precursor" in subsystem Peptidoglycan Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (263 amino acids)

>CSW01_04850 septal ring lytic transglycosylase RlpA (Vibrio cholerae E7946 ATCC 55056)
MNRIYLYLLIVLILAGCSSPGGRYDMSDDQAPDTPLSVEHIEDAHPQYEPYSFGGNKDYN
LRGKSYRIIKNPKGFTESGKASWYGKKFHGHLTSNGEIYDMYSMTAAHKTLPIPSYVKVT
NTDNGKSTVVRVNDRGPFHDGRIIDLSYAAAYKIGVVQAGTANVRIEVITVDKPTKPRPK
SKNNALEYVIQVVSSQHIERVRTLAQNLGQNLSAPSFVESTNNTHRLFLGPFTDDDLTQT
LLEQVKSAGYDSAFIKTINKRAK