Protein Info for CSW01_04770 in Vibrio cholerae E7946 ATCC 55056

Annotation: hemolysin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 957 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF17945: Crystall_4" amino acids 29 to 118 (90 residues), 143 bits, see alignment E=6.4e-46 amino acids 126 to 215 (90 residues), 153.6 bits, see alignment E=3.1e-49 PF13517: FG-GAP_3" amino acids 317 to 376 (60 residues), 30.2 bits, see alignment 1.1e-10 PF16458: Beta-prism_lec" amino acids 507 to 637 (131 residues), 241.2 bits, see alignment E=5.7e-76 amino acids 823 to 955 (133 residues), 132.6 bits, see alignment E=2.1e-42

Best Hits

KEGG orthology group: None (inferred from 100% identity to vco:VC0395_A0455)

Predicted SEED Role

"Hemolysin-related protein RbmC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (957 amino acids)

>CSW01_04770 hemolysin (Vibrio cholerae E7946 ATCC 55056)
MTSHYIALAVGLLSLSSNVVQATTNEAEGCIISRLNGEKYCLKVGERSGYSLPSWIYAHP
VDVQAPSGVSVMLSDWDNLSYNRLAVFDRYTGNEDLKNVKAYNGAYLDFSKPRSMRVLAS
ETYPEACIVSRQTGERFCLKEGERSGYSLPAYIYGHEVDVEAPLGLGVMLSDWDNLSYNR
LAVFGGNTQNEQMRAVKAYNGETLDFSKPRSMRVVPYDGDSSALNMKLKWSWQGSAFQPN
SNQVMVTPIVAQLNDDNGDGKIDEKDVADLIVVTFEGNKYANGGLVRALSGVDGSELWSY
ANGGVIADARYSPAVGDLDGDGIVEIVTTNNRDQFITILDNQGNIKKQIPTTESGWRIVG
DITLADLDHDGSVEILAADGVYNYHSGLVFNHPWAPSSINVDVDGDQQQEVFSGGTLFQN
NGAINWQYQANDAVWFSSLVNLDNDAEPEIVASVPATFATGDNARFAVLEHDGTIKWEIN
NTANPGGGVQAVSNFLGKAQAVETSEFSKVYGYQPNNNPASIALAVDGKISVRSGFAIDA
IGASASTLVGGTGGNLNAAVNVKDIKAIDLTWGKYYWGGYHLLALDFRMSNGSVISMGSK
NYAYSKQTERFTVPAGSRIKGIKAWTAGWLLDGVQFELATQNGTNDLDVKGIVYAGYAAV
DMYNSKGERVWSVANDDTGSGKIGVSAYDFDNDGIDEVLVQDHARVRVLDGKTGKERASL
AHSTATLWEYPIVVDLEGDNNAELIVAANDFDRQYSINHGVYVYQSADSSKPWKNATRIW
NQHAFHLTNINQDGTLPTFVEPSWLSHNTYRSSTLRAAVGGESPIFGYSNTQQSQRVVTA
DNLMYLRSGFAIDAIGTTVNNLVGGPVQGTNGGVLRAPIALDQLQSVEVTSGLYNWGGYH
IVAIKFTMKDGSSVLLGSTHYASNKKVETYTVPQGKRIKQINVWTGGWLVEGFQFVY